Investigative Dermatology and Venereology Research
Aggressive Lentigo Maligna Successfully Treated with Imiquimod 5%: A Case Report
- 1Department of Plastic Surgery, Vejle Hospital, Odense University Hospital, Denmark
- 2Department of Dermatology, Aarhus University Hospital, Denmark
Jens Holm, Department of Plastic Surgery, Vejle Hospital, Odense University Hospital, Denmark, E-mail: firstname.lastname@example.org
Holm, L., et al. Aggressive Lentigo Maligna successfully treated with Imiquimod 5%: A Case Report. (2016) Invest Dermatol Venereol Res 2(2): 1-3.
© 2016 Holm, L. This is an Open access article distributed under the terms of Creative Commons Attribution 4.0 International License.
KeywordsLentigo maligna; Imiquimod; Lentigo malignant melanoma; Case report
The use of the topical Imiquimod (IMQ) 5% cream as a non-surgical alternative to melanoma in situ (MIS) and Lentigo Maligna (LM) is still controversial. Several case reports on this subject are available, but no general consensus exists regarding the efficacy of IMQ for the treatment of MIS.
Here we present a case of a patient successfully treated with topical IMQ 5% for persistent and aggressive LM despite repetitive surgery. In conclusion, IMQ appears to be a safe alternative to surgery in treating MIS; however, more studies are needed to more precisely determine its role in this specific application.