Journal of Gastrointestinal Disorders and Liver function
Primarysplenic Large Cell B Lymphoma: Case Report
Department of Medical Oncology, National Institute of Oncology, Rabat, Morocco
Asmaa Lakhdissi, Department of Medical Oncology, National Institute of Oncology, Rabat, Morocco, E-mail: email@example.com
Lakhdissi, A,. et. al. Primarysplenic Large Cell B Lymphoma: Case Report. (2016) J Gastro Dis Liver Func 2(2): 1- 4.
© 2016 Lakhdissi, A. This is an Open access article distributed under the terms of Creative Commons Attribution 4.0 International License.
KeywordsPrimary splenic lymphoma; Splenectomy; Chemotherapy
Background: Primary splenic lymphoma is a rare disease with heterogeneous definition, compromising less than 1% of non-Hodgkin’s lymphoma.
Case presentation: We are reporting a case of 50 year old man who presented splenomegaly, fever, weight loss and night sweats. The investigations revealed a splenomegaly with splenic lesion which cancorrespond to abscess. The patient underwent splenectomy for definitive diagnosis and treatment. Diagnosis of primary diffuse large B cell lymphoma of the spleen was made and confirmed by immunochemistry and the patient received 6 cycles of RCHOP (Rituximab cyclophosphamide Adriamycin vincristine prednisone) and he is currently well and in complete remission more than 1 year after diagnosis.
Conclusion: Primary splenic lymphoma is rare; splenectomy is an important step in its diagnosis and treatment. Early splenectomy combined with chemotherapy is an optimal strategy.