Serafim  Papadimitriou

Herrera Guillermo A

Professor

biography

Dr. Herrera is a researcher, surgical pathologist and a nephropathologist with over 30 years of experience in renal pathology and over 25 years of basic research on renal damage. Dr. Herrera is an expert in renal damage in plasma cell dyscrasias. In 2007 he published The Kidney in Plasma Cell Dyscrasias, a comprehensive, state-of-the-art view on the subject and more recently edited another book titled Experimental Models for Renal Disease. He has acquired international prominence as a result of his innovative studies in the field of renal amyloidosis. The animal model of renal AL-amyloidogenesis created in his laboratory in collaboration with Dr. Jiamin Teng is the only one available currently and has been used to elucidate mechanisms involved in mesangial damage and repair. His research interests include the effects of monoclonal light chains on the kidney and immunolabeling at the ultrastructural level. Dr. Herrera sits on multiple national panels and has been the invited guest lecturer in over 260 domestic and international venues. He has authored more than 120 articles and chapters in renal pathology. He has received the Tatiana T. Antonovych, M.D. Award from the Armed Forces Institute of Pathology/American Registry of Pathology for contributions to renal pathology and the Distinguished Scientist Award for contributions to science from the University of South Alabama Health Sciences Center. Dr. Herrera is a member of a number of professional societies, including the American Society of Nephrology where he is a Fellow, the International Society of Nephrology and the United States and Canadian Academy of Pathology. He was the President of the Society for Ultrastructural Pathology (2010-2011) and is currently President of the Renal Pathology Society (2012)

 

Area of Interest

1.Light chains and the kidney
2. Amyloidosis
3. Glomerular pathophysiology


top publication

1.Hutchinson, CA, Batuman, V, Behrens, J, Bridoux, F, Sirac, C, Dispenzieri, A, Herrera, GA, Lachmann, H, Sanders, PW: The pathogenesis and diagnosis of acute kidney injury in multiple myeloma. Nat Rev Nephrol 8: 43-51, 2011.
2.Herrera GA: Renal lesions associated with plasma cell dyscrasias: Practical approach to diagnosis, new concepts, and challenges. Arch Pathol Lab Med 133: 249-267, 2009.
3.Herrera, GA, Turbat-Herrera, EA: Renal diseases with organized deposits: An algorithmic approach to classification and diagnosis. Arch Pathol Lab Med 134: 512-531, 2010.
4.Herrera, GA, Turbat-Herrera: Ultrastructural immunolabeling in the diagnosis of monoclonal light and heavy chain-related renal diseases. Ultrastruct Pathol 34: 161-173, 2010.
5.Keeling J, Herrera GA: An in-vitro model of light chain deposition disease. Kidney Int 75: 634-645, 2009.
6.Keeling J, Herrera GA: Matrix metalloproteinases and mesangial remodeling in light chain-related glomerular damage. Kidney Int 68:1590-1603, 2005.
7.Keeling J, Teng J, Herrera GA: AL-amyloidosis and light chain deposition disease light chains induce divergent phenotypic transformations of human mesangial cells. Lab Invest 84:1322-1338, 2004.