Serafim  Papadimitriou

Federica pirrone



Federica Pirrone is a Researcher at the Department of Veterinary Medicine, University of Milan, Italy. She graduated in Veterinary Medicine at the University of Milan in 2003, and became licensed to practice in the same year. She obtained the PhD with scholarship in “Biotechnologies applied to Veterinary and Zootechnical Sciences” at University of Milan in 2007. She is currently Professor in Veterinary Ethology and Animal Welfare within the Course of Physiology and Ethology of Domestic Animals at the University of Milan. Since 2013, she is member of the Ethics Center for Animal Protection of the University of Milan. Dr. Pirrone is member of the European Society of Veterinary Clinical Ethology (ESVCE), the Italian Society of Ethology (SIE) and the Italian Society of Veterinary Physiology (SoFiVet).


Area of Interest

Physiology:- Studies of potential strategies for less invasive mechanical ventilation in ARDS patients - Expression and activation of matrix metalloproteinases under different pathophysiological conditions - Analysis of recumbinant human activated protein C (rhAPC) protection against endotoxic shock - Electromyography and respiratory function in horses - Nitric oxide (NO): a. preparation of a stable injectable NO solution, not commercially available, and validation of NO intravenous administration; b. Study of NO potential endocrine effect: electron spin resonance and chemiluminescence analyses of NO metabolic fate; - Study of novel biomaterials and experimental techniques in cardiovascular surgery.

Animal behavior and welfare:- Analysis of critical factors influencing pet ownership's dynamics - Training of dogs for early detection of human and canine cancer - Monitoring of stress-related physiological and behavioural parameters in dogs involved in activities based on a close human-animal relation - Study of the potential ethological causes of behavioral problems in dogs - Study of exotic animals' intra and interspecific social relationships in captivity

top publication

1. D. D’Ovidio, L. Pierantoni, E. Noviello, F. Pirrone (2016). Sex differences in human-directed social behavior in pet rabbits. Journal of Veterinary Behavior: Clinical Applications and Research. Accepted for publication: 23 Aug 2016. - ISSN:1558-7878 DOI:10.1016/j.jveb.2016.08.072.

2. F. Pirrone, L. Pierantoni, G.Q. Pastorino, M. Albertini (2016). Owner-reported aggressive behavior towards familiar people may be a more prominent occurrence in pet shop traded dogs. Journal of Veterinary Behavior: Clinical Applications and Research 11: 13-17 - ISSN: 1558-7878, doi: 10.1016/j.jveb.2015.11.007.

3. F. Pirrone, L. Pierantoni, S.M. Mazzola, D. Vigo, M. Albertini (2015). Owner and animal factors predict the incidence of, and owner reaction towards, problem behaviors in companion dogs. Journal of Veterinary Behavior: Clinical Applications and Research 10: 295-301 - ISSN: 1558-7878, doi: 10.1016/j.jveb.2015.03.004.

4. F. Pirrone, M. Albertini, S.M. Mazzola, L. Pierantoni, F. Bavagnoli, D. Vigo (2015). Correlation between the size of companion dogs and the profile of the owner: a cross-sectional study in Italy. Dog Behavior, vol. 1, p. 32-43, ISSN: 2421-0684, doi:

5. Zanella, P. Mangili, M. Giani, S. Redaelli, V. Scaravilli, L. Castagna, S. Sosio, F. Pirrone, M. Albertini, N. Patroniti, A. Pesenti (2014). Extracorporeal carbon dioxide removal through ventilation of acidified dialysate : an experimental study. The Journal of Heart and Lung Transplantation, vol. 33, p. 536-541, ISSN: 1053-2498, doi: 10.1016/j.healun.2013.12.006.

6. Zanella, P. Mangili, S. Redaelli, V. Scaravilli, M. Giani, D. Ferlicca, D. Scaccabarozzi, F. Pirrone, M. Albertini, N. Patroniti, A. Pesenti (2014). Regional blood acidification enhances extracorporeal carbon dioxide removal : 48-hour animal study. ANESTHESIOLOGY, vol. 120, p. 416-424, ISSN: 0003-3022, doi: 10.1097/ALN.0000000000000099.

7. C.V. Pastore, F. Pirrone, F. Balzarotti, M. Faustini, L. Pierantoni, M. Albertini (2011). Evaluation of physiological and behavioral stress-dependent parameters in agility dogs., Journal of Veterinary Behavior: Clinical Applications and Research vol. 6, p. 188-194, ISSN: 1558-7878, doi: 10.1016/j.jveb.2011.01.001.

8. C.V. Pastore, F. Pirrone, S. Mazzola, M. Rizzi, M. Viola, G. Sironi, M. Albertini (2011). Mechanical ventilation and volutrauma : study in vivo of a healthy pig model. Biological Research, vol. 44, p. 219-227, ISSN: 0716-9760, doi: 10.4067/S0716-97602011000300002.

9. L. Pierantoni, M. Albertini, F. Pirrone (2011). Prevalence of owner-reported behaviours in dogs separated from the litter at two different ages. Veterinary Record, vol. 169, p. 468-473, ISSN: 0042-4900, doi: 10.1136/vr.d4967.

10. A. Zanella, N. Patroniti, S. Isgro, M. Albertini, M. Costanzi, F. Pirrone, V. Scaravilli, B. Vergnano, A. Pesenti (2009). Blood acidification enhances carbon dioxide removal of membrane lung : an experimental study. Intensive Care Medicine, vol. 35, p. 1484-1487, ISSN: 0342-4642, doi: 10.1007/s00134-009-1513-5.

11. F. Pirrone, C.V. Pastore, S. Mazzola, M. Albertini (2009). In vivo study of the behaviour of matrix metalloproteinases (MMP-2, MMP-9) in mechanical, hypoxic and septic-induced acute lung injury. Veterinary Research Communications, vol. 33, p. 121-124, ISSN: 0165-7380, doi: 10.1007/s11259-009-9255-y.

12. Pastore, C., Pirrone, F., Mazzola, S., Clement, M.G., Albertini, M. (2008). Mechanical ventilation and volutrauma: Pros and cons of high lung volumes. Veterinary Research Communications, vol. 32 (suppl. 1): pp. 163-165 - ISSN:0165-7380, doi:10.1007/s11259-008-9112-4.

13. F. Pirrone, S.M. Mazzola, C.V. Pastore, S. Paltrinieri, G. Sironi, P. Riccaboni, M. Viola, A. Passi, M.G. Clement, M. Albertini (2008). Activated protein C protection from lung inflammation in endotoxin-induced injury. Experimental Biology And Medicine, vol. 233, p. 1462-1468 - ISSN: 1535-3702, doi: 10.3181/0802-RM-74.

14. F. Pirrone, M. Albertini, M.G. Clement, C.L. Lafortuna (2007). Respiratory mechanics in standardbred horses with sub-clinical inflammatory airway disease (IAD) and poor athletic performance. The Veterinary Journal, vol. 173, p. 144-150 - ISSN: 1090-0233, doi: 10.1016/j.tvjl.2005.07.020.