Serafim  Papadimitriou

Nilesh wagh



Senior Radiochemist Scientist- Radiomedix Inc, Houston                                                                    2014-Present

Ø   Senior radiochemist with over six years experience in radiopharmaceutical discovery and involved in programs from earliest discovery stages into clinical development.  

Ø    Characterization of Small molecules (NCE) and Peptides using Mass spectroscopy, HPLC and TLC.

Ø    Well-developed presentational, management skill and reporting to the   research group and management.

Elder Pharmaceuticals, Navi Mumbai, India Research and Development Executive                             2009-2010                                                                           

Ø  Worked on development of new chemical entities

Ø  In-depth experience on FT-IR, NMR, MS-MS and X -ray crystallography.

Ø  Successfully completed filling of 3 patent applications. Instrumental in writing provisional patent specification drafting.

Ø  Postdoctoral Research Associate (Radiochemistry)

Department of Pharmaceutical Sciences, University of Nebraska Medical Center. USA


Ø  Ph.D (Pharmaceutical Chemistry)


Bharati Vidyapeeth University, Poona College of Pharmacy, Pune. India.



Area of Interest


top publication

 Zhengyuan Zhou, Nilesh K. Wagh, Sunny M. Ogbomo, Wen Shi, Yinnong Jia, Susan K. Brusnahan, Jered C. Garrison. In vivo evaluation of an 111In-labeled hypoxia enhanced 111In-bombesin conjugates for specific targeting of BB2 receptors on human prostate cancers. Journal of Nuclear Medicine. 2013 54:1605-1612.  Sunny M. Ogbomo, Wen Shi, Nilesh K Wagh, Zhengyuan

Zhou, Susan K. Brusnahan, Jered C. Garrison 177Lu- labeled HPMA Copolymers Utilizing Cathepsin B and S Cleavable Linkers: Synthesis, Characterization and Preliminary In Vivo Investigation in a Pancreatic Cancer Model. Nuclear Medicine and Biology. 2013 Jul;40(5):606- 17. 

W Shi, SM Ogbomo, NK Wagh, Z Zhou, Y Jia, SK Brusnahan, JC Garrison The influence of linker length on the properties of cathepsin S cleavable 177 Lu-labeled HPMA copolymers for pancreatic cancer imaging Biomaterials 2014 , 35 (22), 5760-5770

 Y Jia, W Shi, Z Zhou, NK Wagh, W Fan, SK Brusnahan, JC Garrison Evaluation of DOTA-chelated neurotensin analogs with spacer-enhanced biological performance for neurotensin-receptor-1-positive tumor targeting  Nuclear medicine and biology2015 42 (11), 816-823

Nilesh K. Wagh, Zhengyuan Zhou, Sunny M. Ogbomo, Wen Shi, Susan K. Brusnahan, Jered C. Garrison. Development of Hypoxia Enhanced 111In-labeled Bombesin Conjugates: Design, Synthesis and In Vitro Evaluation in PC-3 Human Prostate Cancer. Bioconjugate Chemistry 2012, 23 (3), 527–537. 

Sachin L. Badole, Sagar P. Mahamuni, Pranita P. Bagul, Arvindkumar E. Ghule, Subhash L. Bodhankar, Chandrashekhar G. Raut, Evans C Coutinho, Nilesh K Wagh.Cycloart-23-ene-3β, 25-diol stimulates GLP-1 (7–36) amide secretion in streptozotocin–nicotinamide induced diabetic Sprague Dawley rats: A mechanistic approach. European journal of pharmacology, 2013,698(1-3) ,470-479

Nilesh K. Wagh, Hemantkumar S. Deokar, Badal S. Rathi, Subhash L. Bodhankar, Vithal M. Kulkarni. Anti- inflammatory and Analgesic Activity of 4’-methylbiphenyl-2- (Substituted Phenyl) Carboxamide Analogs In Animal Models of Inflammation Pharmacologyonline 2006, 2, 1-13.

 Nilesh K. Wagh, Hemantkumar S. Deokar, Dhanshri C. Juvale, Shivajirao S. Kadam, Vithal M. Kulkarni. 3D- QSAR of histone deacetylase inhibitors as anticancer agents by genetic function approximation. Indian Journal of Biochemistry & Biophysics. 2006, 43,360-371.

Dhanshri C. Juvale, Vishal V. Kulkarni, Hemantkumar S. Deokar, Nilesh K.Wagh, Subhash B. Padhye and Vithal M. Kulkarni. 3D- QSAR analysis of histone deacetylase inhibitors: hydroxamate analogues Organic Biomolecular Chemistry, 2006 4, 2858-2868.

Badal. S. Rathi, Nilesh. K. Wagh, Subhash. L. Bodhankar and Vithal. M. Kulkarni. Evaluation of Anti- Inflammatory and Analgesic Activity of a New Class of Biphenyl Analogs in Animal Models of Inflammation. Arzneim.-Forsch./Drug Res. 2006, 56, No.9, 640-646

Ujashkumar a. Shah, nilesh k. Wagh, hemantkumar s. Deokar, shivajirao s. Kadam and vithal m. Kulkarni* design, synthesis, pharmacological screening and molecular docking of biphenyl analogues as antiinflammatory agents International Journal of Pharma and Bio Sciences Vol.1/Issue-4/Oct-Dec.2010 501-511

Ujashkumar a. Shah, nilesh k. Wagh, hemantkumar s. Deokar, shivajirao s. Kadam and vithal m. Kulkarni 3d-qsar of biphenyl analogues as anti-inflammatory agents by genetic function approximation (gfa)[part-ii] International Journal of Pharma and Bio Sciences Vol.1/Issue-4/Oct-Dec.2010 512-522