Association between Blood Lead (BLL) Level Concentration and Tremor in highly exposed battery workers at manufacturing Industries of Lucknow city
V Atam1, P kumar2, A Kumar3, Isha Atam1 H B Sharma4, N Sharma1
Affiliation
1Department of Medicine, King George’s Medical University Lucknow, UP, India
2Department of Physiology, King George’s Medical University Lucknow, UP, India
3Department of Forensic Medicine & Toxicology, King George’s Medical University Lucknow, UP, India
4Department of Obstetrics & Gynecology, King George’s Medical University Lucknow, UP, India
Corresponding Author
Shyam Vinay Sharma, Research Scholar, Department of Medicine, King George’s Medical University, UP, Lucknow, India; E-mail: sv_sharmakgmu@rediffmail.com
Citation
Sharma, S.V., et al. Association between Blood Lead (BLL) Level Concentration and Tremor in Highly Exposed Battery Workers at Manufacturing Industries of Lucknow City. (2018) Int J Neurol Brain Dis 5(1): 6- 10.
Copy rights
© 2018 Sharma, S.V. This is an Open access article distributed under the terms of Creative Commons Attribution 4.0 International License.
Keywords
Abstract
Objective: Tremor is one of the most commonly encountered neurological problems, and it may be a feature of a variety of neurological diseases. Despite tremor among very common in elderly, there are very limited data on the role of environmental exposures that are potentially modifiable. Lead is an environmentally persistent toxicant that may cause various types of physiological and pathological disorders in human beings.
Material and Method: The study was conducted on 135 subjects divided into study and control groups. The inclusion criteria for study group were age between 20 to 40 years, exposure to Lead (Pb) more than five years, BMI less than 25 and having no any systemic diseases. The lead exposed subjects were taken from battery workshops & industries of Lucknow city. Recruited subject were explained about the study protocol.
Result: The mean Pb level in cases were found 35.04 ± 13.39 (μg/dl) and control were 5.53 ± 1.75 (μg/dl) which are significantly (p < 0.001) different and exceptionally higher as compared to controls. Higher value of lead (Pb) level disturbed the balancing power and motor nerve of brain therefore tremor are developed in arm and leg.
Conclusion:The battery workers who were exposed ≥10 years have increased blood lead (Pb) level and decrease hemoglobin level in body and suffering from tremor disorder, who suggest for risk of moderate and severe neurological manifestation like tremor.
