Journal of Marine Biology and AquacultureJournal of Marine Biology and AquacultureJournal of Marine Biology and AquacultureJournal of Marine Biology and Aquaculture2381-0750Ommega Online PublishersNew Jersey, USA122410.15436/2381-0750.17.1224Research ArticleComparison of Different Membrane Filtration Systems for Recovering Active Phenolic Compounds from the European Spread Macroalga Sargassum muticumComparison of Different Membrane Filtration Systems for Recovering Active Phenolic Compounds from the European Spread Macroalga Sargassum muticumLaurentVANDANJON 1University of Nantes GEPEA UMR CNRS 6144 IUML FR CNRS n deg 3473 F-44600 Saint-Nazaire 2University of South-Brittany LBCM EA 3884 IUEM F-56000 Vannes France 3University of Western Brittany LEMAR UMR 6539 IUEM F-29280 Plouzan eacute France Editor* E-mail: laurent.vandanjon@univ-ubs.fr
The authors have declared that no competing interests exist.
20173003201731JMBA-16-RA-122415112016230120172017Creative Commons Attribution LicenseThis is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. nbsp emsp emsp Sargassum muticum is an invasive macroalga that uncontrollable widely grows on the European Atlantic coasts This macroalga is particularly rich in phenolics phlorotannins presenting biological activities such as antioxidant radical-scavenging antibacterial photoprotective properties etc Among the diversity of metabolites produced by the species phenolic compounds could constitute one of the potential ways of valorization of Sargassum muticum emsp emsp For the needs of the study algae were harvested along a latitudinal gradient in Norway Ireland France Spain and Portugal emsp emsp After extraction the highest phenolic contents and bioactivities were measured for the samples coming from Norway and Portugal Consequently both these countries have been retained in the present work emsp emsp The extracts are composed of a ldquo pool rdquo of phenolic compounds of molecular weight varying according to the literature from 126 Da phloroglucinol to 650 kDa But the most common compounds are comprised between 10 and 100 kDa With the aim of concentrating and eventually fractionating i e isolating the most active fractions the phenolic extracts of Sargassum muticum a few membranes of Molecular Weight Cut-Off 10 kDa were chosen These membranes were tested by using different technologies ultrafiltration centrifugal tube and dialysis emsp emsp Results show that there is no significant activity in the permeates signifying that the retention rate is about 100 for the active fractions Concerning the retentates results show clearly an increase of the total phenolic contents as well as antioxidant and radical scavenging activities The best performances are obtained with the centrifugal tubes using 10 kDa membranes 10