Journal of Dentistry and Oral CareJournal of Dentistry and Oral CareJournal of Dentistry and Oral CareJournal of Dentistry and Oral Care2379-1705Ommega Online PublishersNew Jersey, USA138110.15436/2379-1705.17.1381Research ArticleEffectiveness of Probiotic Lactobacillus salivarius WB21 Tablets on Oral Malodor among Patients Attending Dental Institution in Mysuru City, India-An Open Label Pilot Trial Effectiveness of Probiotic Lactobacillus salivarius WB21 Tablets on Oral Malodor among Patients Attending Dental Institution in Mysuru City, India-An Open Label Pilot Trial PriyankaSharma 1Department of Public Health Dentistry JSS Dental College and Hospital Jagadguru Sri Shivarathreeshwara University Mysuru India 2Department of Preventive and Public Health Dentistry Fukuoka Dental College Tamura Sawara-ku Fukuoka Japan 3Department of General Dentistry Fukuoka Dental College Tamura Sawara-ku Fukuoka Japan 4Tanabe Clinic for Preservative Dentistry Mizutani Higashi-ku Fukuoka Japan 5Department of Periodontics JSS Dental College and Hospital Jagadguru Sri Shivarathreeshwara University Mysuru India Editor* E-mail: priyankasharmamds@gmail.com
The authors have declared that no competing interests exist.
20170606201732JDOC-17-RA-138122022017010620172017Creative Commons Attribution LicenseThis is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. nbsp Aim To evaluate the effectiveness of Lactobacillus salivarius WB21 tablets on oral malodor among adult patients attending a dental institution in Mysuru city India Methods This open label trial was conducted in September 2015 by a single calibrated principal investigator on 21 adult patients with genuine halitosis With prior informed consent participants were given 2 0 times 109 L salivarius WB21 and xylitol in tablet form to be consumed three times after food daily Oral malodor and clinical parameters were evaluated at the baseline and after 2 and 4 weeks Genuine halitosis was further classified to physiological and pathological halitosis Results Bleeding on probing tongue coating score and stimulated salivary flow were significantly improved at 2 weeks compared to baseline levels A significant decrease in plaque index average probing pocket depth and organoleptic score was observed at 4 weeks The changes during 4 weeks in all clinical parameters were significantly greater in the participants with pathological halitosis compared to physiological halitosis Conclusions Oral administration of probiotic Lactobacilli improved clinical and oral malodor parameters Further large-scale randomized clinical trials are necessary to explain the effectiveness of probiotics in management of oral malodor and periodontal diseases 10