International Journal of Cancer and Oncology International Journal of Cancer and Oncology International Journal of Cancer and Oncology International Journal of Cancer and Oncology 2377-0902Ommega Online PublishersNew Jersey, USA159810.15436/2377-0902.17.1598Research ArticleSolitary Fibrous Tumour of the Pleura and Paraneoplastic Symptoms: A Case Report and Literature ReviewSolitary Fibrous Tumour of the Pleura and Paraneoplastic Symptoms: A Case Report and Literature ReviewUffeBodtger 1Institute for Regional Health Research University of Southern Denmark Odense Denmark 2Department of Pulmonology Naestved Hospital Nastved Denmark 3Department of Pulmonology Zealand University Hospital Roskilde Roskilde Denmark Editor* E-mail: ubt@regionsjaelland.dk
The authors have declared that no competing interests exist.
20172410201742IJCO-17-CR-159811072017181020172017Creative Commons Attribution LicenseThis is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. nbsp Background Solitary fibrous tumors of the pleura SFTP are rare neoplasms deriving from mesenchymal cells They are mostly benign and may be accompanied by paraneoplastic syndromes particularly hypoglycaemia and hypertrophic pulmonary osteoarthropathy HPO Methods A Case Report of a patient with HPO preceding respiratory symptoms secondary to a huge SFTP which was surgically removed and found benign A literature search was conducted on PubMed using the MeSH terms secondary hypertrophic osteoarthropathy solitary fibrous tumor and solitary fibrous tumor of the pleura Searches were limited to abstract full text and English language Articles from 1946 to 2016 were browsed and relevant articles extracted and reviewed Results Our case patient experienced only partial remission of HPO despite benign histology and no signs of recurrence 3 years after surgery This is in contrast to the literature This report reviews the various mechanisms suggested to be involved in development of HPO the humoral immunologic and neurogenic theory Conclusion SFTP has almost all characteristics for development of HPO but all these resolves after surgical resection Recurrence of HPO is thus indicative of SFTP recurrence which must be explored thoroughly 10