Journal of Anesthesia and SurgeryJournal of Anesthesia and SurgeryJournal of Anesthesia and SurgeryJournal of Anesthesia and Surgery2377-1364Ommega Online PublishersNew Jersey, USA162210.15436/2377-1364.17.081Research ArticleHypereosinophilia-and-Intraoperative-Complications-under-General-Anesthesia-in-Surgical-Patients-Aged-12-Years-or-More-an-ObservationHypereosinophilia-and-Intraoperative-Complications-under-General-Anesthesia-in-Surgical-Patients-Aged-12-Years-or-More-an-ObservationHabib Md ReazaulKarimAssistant Professor Department of Anaesthesiology Andaman and Nicobar Islands Institute of Medical Sciences amp GB Pant Hospital Port Blair IndiaEditor* E-mail: drhabibkarim@gmail.com
The authors have declared that no competing interests exist.
20173108201742JAS-17-RA-1622/08131072017290820172017Creative Commons Attribution LicenseThis is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. nbsp Background Hypereosinophilia HE is a relatively commoner and previously has been shown to be associated with several adverse effects in intraoperative and immediate postoperative period in anesthetic practice However recent scientific literature in this aspect is very scarce Aim The present study was aimed to assess the frequency of HE and incidences of notable intraoperative adverse events in such patients Methods The present study was conducted in a tertiary care teaching hospital during December 2016 to June 2017 Files of all patients aged 12 years and more attending preanesthetic evaluation clinic was screened for the presence of HE Anesthetic management of these patients was then observed and adverse events like respiratory spasms urticaria drug reactions etc noted Data were presented in absolute numbers and percentage scale INSTAT software was used for statistical analysis purpose Results A total of 1012 patients were included 74 7 31 were having absolute Eosinophil counts AEC gt 500 x 109 l Eosinophilia was more among male 58 11 and significantly more frequent in children than adults 17 39 versus 6 83 p 0 015 The AEC of hypereosinophilic patients ranged from 502 to 4030 times 109 l Medicine consultation was taken in two cases while six cases were prescribed antihelminthic and antihistaminic drug by anesthesiologist in preoperative period The treatment was effective in reducing AEC by an average of 1191 5 times 109 l Twenty three out of 27 patients who were managed with general anesthesia were observed for HE related complication No notable complication attributable to HE was found Conclusion HE is very common even in adult surgical patients mostly asymptomatic and idiopathic HES is however rare Deworming and antihistaminic treatment was effective in reducing AEC in patients with marked HE GA with currently used agents appear to be safe and without much adverse effects if any in hypereosinophilic patients 10