Journal of Stem Cell and Regenerative BiologyJournal of Stem Cell and Regenerative BiologyJournal of Stem Cell and Regenerative BiologyJournal of Stem Cell and Regenerative Biology2471-0598Ommega Online PublishersNew Jersey, USA187910.15436/2471-0598.18.1879Research Article Reconstruction of Lower Jaw by Iliac Bone Graft, Experimental Study on Rabbit and Role of Mesenchymal Stem Cells Reconstruction of Lower Jaw by Iliac Bone Graft, Experimental Study on Rabbit and Role of Mesenchymal Stem CellsRAJAKUMMOONA1FDSRCS Eng FICD of Maxillofacial Surgery Iraqi Board for Medical Specializations Medical City Baghdad Iraq2FICM of Maxillofacial Surgeons Al Wasty Hospital for Reconstructive and Plastic Surgery Baghdad IraqEditor* E-mail: dr_raja_kummoona@yahoo.com
The authors have declared that no competing interests exist.
20181406201841JSRB-18-RA-187901052018060620182018Creative Commons Attribution LicenseThis is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. nbsp emsp emsp In this research twelve young male Rabbits age of 3 months are weighted 1 25 kg divided in two groups of 5 Rabbits and 2 Rabbits were used as control They were subjected to surgical osteoctomy by excising bone 1 5cm from the body of the mandible and bone graft of 2cm harvested from the iliac crest The graft was fixed by soft stainless steel wire of 0 25 mm post-operative systemic antibiotic of ceftriaxone of 20 mg kg IM of body weight for six days prescribed oxidized regenerated cellulose mesh was used to cover the graft of group B emsp emsp After 3 months the experiment was terminated the result were 2 Rabbits passed one Rabbit end with infection and one with slight injury to Sciatic nerve without effect on mastication The dyed Rabbits and one with infection were excluded from this experiment emsp emsp The cytological changes of bone grafting showed formation of healthy granulation tissue with mesenchymal stem cells derived from bone marrow of bony segments of the mandible with platelets growth factor PDGF and from periosteum and covering muscles with large amount of fibroblasts with tiny blood vessels Osteoblast was noticed more with chondrocyte and osteoid tissue with bone graft that covered by Surgical mesh oxidized regenerated cellulose soaked in blood and covered bone graft of group B to get faster healing in group B than in group A The aim of this research to understand the cytological changes that occurred in the graft and recipient area 10