Journal of Heart and Cardiology Journal of Heart and Cardiology Journal of Heart and Cardiology Journal of Heart and Cardiology 2378-6914Ommega Online PublishersNew Jersey, USA2610 10.15436/2378-6914.19.2610Research ArticleRelationship between initial high-sensitivity cardiac troponin-T morbidity and mortality in patients after ST-elevation Myocardial Infarction in Erbil City, IraqRelationship between initial high-sensitivity cardiac troponin-T morbidity and mortality in patients after ST-elevation Myocardial Infarction in Erbil City, IraqNicolaKing1Hawler Medical University Medical College Department of Medicine Erbil City Iraq 2School of Biomedical Sciences Faculty of Health Medicine Dentistry and Human Sciences University of Plymouth Plymouth PL4 8AA UKEditor* E-mail: nicola.king@plymouth.ac.uk
The authors have declared that no competing interests exist.
20192011201961JHC-19-RA-261002102019151120192019Creative Commons Attribution LicenseThis is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.Background ST-segment elevation myocardial infarction STEMI patients treated with primary percutaneous intervention PPCI are at a high risk of death and MACE Major Adverse Cardiovascular Events One method to stratify these patients rsquo risk could be high-sensitivity cardiac troponin-T hs-cTnT Unfortunately data using this approach is limited The aim of this study was to investigate whether there is a correlation between initial levels of cTnT in STEMI patients with MACE nbsp Methods Initial hs-cTnT levels were measured in 167 patients with STEMI undergoing PPCI Patients were divided into 2 groups group A hs-cTnT below the median 83 patients group B hs-cTnT above the median 84 patients Patients were followed up for 2 years investigating mortality and MACE nbsp Results The median value of initial hs-cTnT was 100 ng L The mean hs-cTnT was 52 plusmn 26 ng L in group A and 548 plusmn 458 ng L in group B 18 10 8 patients died during follow-up 13 15 5 in group B compared to only 5 6 ingroup A P lt 0 05 Further analysis showed that non-surviving patients were older more likely to be female had more diabetes mellitus more hypertension and more diffuse coronary artery disease They also had worse outcomes such as heart failure increased rates of recurrent chest pain readmissions and other infrequent complications such as complete heart block renal impairment reinfarction stent thrombosis and upper gastrointestinal tract bleeding nbsp Conclusions Increased initial hs-cTnT levels are associated with a higher risk of mortality and morbidity at 2-year follow up in patients from Erbil with STEMI undergoing PPCI 10