Journal of Marine Biology and AquacultureJournal of Marine Biology and AquacultureJournal of Marine Biology and AquacultureJournal of Marine Biology and Aquaculture2381-0750Ommega Online PublishersNew Jersey, USA3010Research ArticleScreening of Potential Bioactive Compounds from Padina gymnospora found in the Coast of St. Martin Island of BangladeshScreening of Potential Bioactive Compounds from Padina gymnospora found in the Coast of St. Martin Island of BangladeshMOHAMMAD NAZIRHOSSAINDepartment of Genetic Engineering and Biotechnology Faculty of Earth and Ocean Science Bangabandhu Sheikh Mujibur Rahman Maritime University Dhaka-1216 Bangladesh Editor* E-mail: nazir.geb@bsmrmu.edu.bd
The authors have declared that no competing interests exist.
20210103202161JMBA-21-RA-301030102020280220212021Creative Commons Attribution LicenseThis is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.Seaweed is the most popular marine resource which plays an important role biologically in different research area in the world In spite of this significance of seaweed very few algae based studies have been conducted in Bangladesh For the first time this study aimed to find out the potential bioactivity of Padina gymnospora collected from the St Martin Island of Bangladesh The present study investigated the potential bioactivities of Padina gymnospora Initially Study subject was extracted with five different solvents Crude extracts were screened for crucial phytochemicals DPPH radical scavenging activity was implemented for antioxidant test The antibacterial activities were examined by agar well diffusion method Cytotoxic test were conducted following Brine Shrimp Lethality Assay The result showed that Methanol and ethanol crude extracts exhibited the presence of the highest number of bioactive compounds The highest inhibition 48 28 plusmn 47 along with a significant IC50 value of 369 99 micro g ml p lt 0 05 was found in ethanol crude Isopropanol followed by methanol crude extract has shown strong activity against B cereus S aureus Chloroform crude extract was highly effective against Salmonella species while ethanol crude extract showed the highest activity against S aureus Salmonella species and S hominis It is also recorded that the isopropanol and chloroform crude extracts showed highly cytotoxicity IC50 lt 100 mu g ml p lt 0 05 The present findings suggested that Padina gymnospora has substantial bioactivity due to the presence of phenolic compounds flavonoids steroids and other secondary metabolites 10