International Journal of Cancer and Oncology International Journal of Cancer and Oncology International Journal of Cancer and Oncology International Journal of Cancer and Oncology 2377-0902Ommega Online PublishersNew Jersey, USA10.15436/2377-0902.22.3871Research ArticleCytologic Assessment of Intraductal Papillary Neoplasm of the Bile Duct (IPNB): Case ReportCytologic Assessment of Intraductal Papillary Neoplasm of the Bile Duct (IPNB): Case ReportsherehanZada Department of Pathology and Laboratory University of California IrvineEditor* E-mail: sherehaz@uci.edu
The authors have declared that no competing interests exist.
20220512202271IJCO-22-CR-387130112022011220222022Creative Commons Attribution LicenseThis is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.The intraductal papillary neoplasm of the bile duct IPNB is an uncommon entity that has been encountered in the extrahepatic and or intrahepatic bile ducts This lesion is a precursor lesion that can affect the biliary epithelium with a high rate of associated dysplasia invasive carcinoma Herein we report a case of intraductal papillary neoplasm of the bile duct that has been diagnosed based upon the cytology specimen A 78-year-old male presented with an incidental liver hilum mass during an imaging study The cytological evaluation revealed clusters of biliary epithelial cells with papillary architecture and fibrovascular cores The biliary epithelial cells demonstrate low and focal high-grade dysplasia which in conjunction with imaging studies are indicative of an intraductal papillary neoplasm of the bile duct The histologic examination of the excised specimen later confirmed the primary cytology findings To our knowledge documentation of the diagnosis of intraductal papillary neoplasm of the bile duct especially from a cytologic evaluation standpoint remains limited and will herein is elucidated 10