Journal of Gastrointestinal Disorders and Liver functionJournal of Gastrointestinal Disorders and Liver functionJournal of Gastrointestinal Disorders and Liver functionJournal of Gastrointestinal Disorders and Liver function2471-0601Ommega Online PublishersNew Jersey, USA76510.15436/2471-0601.16.765Research ArticlePrimarysplenic Large Cell B Lymphoma: Case ReportPrimarysplenic Large Cell B Lymphoma: Case ReportAsmaaLakhdissiDepartment of Medical Oncology National Institute of Oncology Rabat MoroccoEditor* E-mail: asmaalakhdissi@gmail.com
The authors have declared that no competing interests exist.
20160804201622JGDLF-16-CR-76531012016040420162016Creative Commons Attribution LicenseThis is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. nbsp Background Primary splenic lymphoma is a rare disease with heterogeneous definition compromising less than 1 of non-Hodgkin rsquo s lymphoma Case presentation We are reporting a case of 50 year old man who presented splenomegaly fever weight loss and night sweats The investigations revealed a splenomegaly with splenic lesion which cancorrespond to abscess The patient underwent splenectomy for definitive diagnosis and treatment Diagnosis of primary diffuse large B cell lymphoma of the spleen was made and confirmed by immunochemistry and the patient received 6 cycles of RCHOP Rituximab cyclophosphamide Adriamycin vincristine prednisone and he is currently well and in complete remission more than 1 year after diagnosis Conclusion Primary splenic lymphoma is rare splenectomy is an important step in its diagnosis and treatment Early splenectomy combined with chemotherapy is an optimal strategy 10