Investigative Dermatology and Venereology ResearchInvestigative Dermatology and Venereology ResearchInvestigative Dermatology and Venereology ResearchInvestigative Dermatology and Venereology Research2381-0858Ommega Online PublishersNew Jersey, USA76910.15436/2381-0858.16.016Research ArticleEpidermolytic Hyperkeratosis: A Case Report from YemenEpidermolytic Hyperkeratosis: A Case Report from YemenMohammad AliAlshami 1Dermatology Department Faculty of Medicine and Health Sciences University Hospital Sana rsquo a University Sana rsquo a Yemen 2Faculty of Dentistry Sana rsquo a University Sana rsquo a Yemen Editor* E-mail: mohammadalshami62@gmail.com
The authors have declared that no competing interests exist.
20160903201621IDVR-16-CR-76902022016040320162016Creative Commons Attribution LicenseThis is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. nbsp emsp emsp Epidermolytic hyperkeratosis is a rare autosomal dominant disorder of cornification with a prevalence of 1 100 000 to 1 300 000 which affect both sexes equally We report the case of a 10-year-old girl who presented to the dermatology clinic with dirty brown corrugated hyperkeratotic plaques involving joint flexures and the trunk She had similar lesions arranged in a cobblestone pattern over the knees elbows and dorsal hands and feet in addition to multiple superficial erosions She had a history of generalized erythroderma and trauma-related blistering at the time of birth All other family members were healthy and had no such skin manifestations 10