International Journal of Neurology and Brain DisordersInternational Journal of Neurology and Brain DisordersInternational Journal of Neurology and Brain DisordersInternational Journal of Neurology and Brain Disorders2377-1348Ommega Online PublishersNew Jersey, USA79510.15436/2377-1348.16.795Research ArticleAn Association of Fragile X Associated Tremor/Ataxia Syndrome (FXTAS) with Three Common Neurological Problems: A ReviewAn Association of Fragile X Associated Tremor/Ataxia Syndrome (FXTAS) with Three Common Neurological Problems: A ReviewHassaan TohidCenter for Mind and Brain University of California Davis United StatesEditor* E-mail: hassaantohid@hotmail.com
The authors have declared that no competing interests exist.
20162508201633IJNBD-16-RA-79526022016210720162016Creative Commons Attribution LicenseThis is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. nbsp Aim To study the association of Fragile X associated tremor ataxia syndrome FXTAS with Alzheimer rsquo s disease and Lewy Body Dementia Method A systematic search was performed in various data bases and journals of Neurology In total over 600 articles were reviewed and out of those 39 were selected based on selection criteria Results FXTAS is associated with Alzheimer rsquo s disease and Lewy Body dementia because so many symptomatic and pathophysiological similarities are found between FXTAS and these two neurodegenerative diseases Conclusion The association of FXTAS with neurodegenerative illnesses like Alzheimer rsquo s disease and Lewy Body dementia is present because of many similarities between them However some dissimilarities do exist and some questions remain in addressing the pathophysiology of this association Therefore we recommend more research in the near future to understand this association to develop and utilize wide-reaching therapies 10