Journal of Diabetes and ObesityJournal of Diabetes and ObesityJournal of Diabetes and ObesityJournal of Diabetes and Obesity2376-0494Ommega Online PublishersNew Jersey, USA83910.15436/2376-0494.16.838Research ArticleClinical Outcomes in Patients with Diabetes Mellitus Using a Medically Supervised Commercial Weight Reduction Program Compared to Standard Care in an Endocrine Specialty ClinicClinical Outcomes in Patients with Diabetes Mellitus Using a Medically Supervised Commercial Weight Reduction Program Compared to Standard Care in an Endocrine Specialty ClinicRyanKennedy 1Division of Endocrinology and Metabolism University of Kentucky Lexington KY 2Department of Statistics University of Kentucky Editor* E-mail: rckennedy@live.com
The authors have declared that no competing interests exist.
20162309201632JDO-16-RA-83928032016200920162016Creative Commons Attribution LicenseThis is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. nbsp Aims To evaluate metabolic and anthropometric changes achieved and maintained by diabetic patients pts in a structured weight loss WL program vs usual care in an endocrine clinic UCG Materials and Methods This retrospective comparison study examined 38 diabetic pts with BMI gt 25 undergoing the active weight loss phase of WL determined by patient goal weight and then followed for 6 months in weight maintenance phase WM Multiple endpoints were assessed at baseline including BMI and hemoglobin A1c A1c Endpoints were reassessed at 6 months in WM The usual care group UCG was obtained through chart review of 26 diabetic pts with BMI gt 25 in an endocrine specialty clinic who completed an education program including lifestyle counseling by a certified diabetic educator Data were analyzed using ANCOVA and protected LSD adjusting for age gender and baseline weight Results Patients showed a change in BMI at 6 months of -6 8 plusmn 0 bsl 44 plusmn 8 4 and -0 7 plusmn 1 1 bsl 35 plusmn 6 2 for HMR reg pts and UCG respectively p lt 0 05 HMR reg pts had 13 4 plusmn 3 WL vs 7 9 plusmn 4 in UCG p 0 34 6 month A1c was similar in HMR pts 7 5 plusmn 2 bsl 8 3 plusmn 1 9 and UCG 7 5 plusmn 2 3 bsl 9 8 plusmn 1 8 HMR reg pts had a reduction of total medication usage of 28 with at least one medication discontinued in 80 of pts while the UCG had only 23 of pts with discontinuation of at least one medication p lt 0 05 Conclusions Compared to CDE-led diabetic education emphasizing lifestyle change pts in an intensive WL program utilizing weekly coaching meal replacements and exercise had a significant decrease in BMI and achieved a similar A1c with reduction in medication requirements 10