Journal of Addiction and DependenceJournal of Addiction and DependenceJournal of Addiction and DependenceJournal of Addiction and Dependence2471-061XOmmega Online PublishersNew Jersey, USA97510.15436/2471-061X-16-025Research ArticleTreatment of Chronic Methadone Dependence with Buprenorphine Treatment of Chronic Methadone Dependence with Buprenorphine Jamshid AhmadiSubstance Abuse Research Center Shiraz University of Medical Sciences Shiraz IranEditor* E-mail: Jamshid_Ahmadi@yahoo.com
The authors have declared that no competing interests exist.
20162507201623JAD-16-RW-975/02520062016210720162016Creative Commons Attribution LicenseThis is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.Background Methadone abuse is a puzzle Objective To uncover the achievement of a single high dose of 64 mg of buprenorphine for the remedy of methadone dependency Results 64 mg of buprenorphine as a single administration can be sufficient for the treatment of methadone dependent patient Discussion Our study indicates that buprenorphine 64 mg as a single dose only can be sufficient for the treatment of methadone withdrawal symptoms So this work may be a substantial addition to the literature Conclusions We can conclude that a single high dose of buprenorphine may be enough for the treatment of methadone withdrawal symptoms 10