Serafim  Papadimitriou

Yang Shun-Fa

professor

biography

Yang is a professor of Institute of Medicine, Chung Shan Medical University, Taiwan. He has received the Ph.D. degree in molecular biology. In particular, his researches have been focused on pharmacology, cancer metastasis, cancer biology, genetic polymorphism and environment risk factors in cancer.

 

Area of Interest

Pharmacology
Cancer metastasis
Cancer biology
Genetic polymorphism and environment risk factors in cancer


top publication

1. Chung TT, Pan MS, Kuo CL, Wong RH, Lin CW, Chen MK, Yang SF*. Impact of RECK gene polymorphisms and environmental factors on oral cancer susceptibility and clinicopathologic characteristics in Taiwan. Carcinogenesis 2011; 32: 1063-1068. (SCI)
2. Hsieh YS, Yang SF, Chen PN, Chu SC, Chen CH, Kuo DY*. Knocking down the transcript of protein kinase C-lambda modulates hypothalamic glutathione peroxidase, melanocortin receptor and neuropeptide Y gene expression in amphetamine-treated rats. Journal of Psychopharmacology 2011; 25: 982-994. Contributed equally as first author (SCI)
3. Wu YC, Wang PH*, Tsai A, Yang SF, Chen SC. Semi-quantitative expression of tissue inhibitor of matrix metalloproteinase-2 in cancer of uterine cervix. Journal of Surgical Oncology 2011; 104: 210-215. (SCI)
4. Chen TY, Li YC, Liu YF, Tsai CM, Hsieh YH, Lin CW, Yang SF, Weng CJ *. Role of MMP14 gene polymorphisms in susceptibility and pathological development to hepatocellular carcinoma. Annals of Surgical Oncology 2011; 18: 2348-2356. (SCI)
5. Wang PH, Ko JL, Yang SF, Tsai HT, Tee YT, Han CP, Lin LY, Chen SC, Shih YT*. Significant relation of tissue inhibitor of matrix metalloproteinase-2 and its combination with matrix metalloproteinase-2 to survival of patients with cancer of uterine cervix. Reproductive Sciences 2011; 18: 798-808. (SCI)
6. Yoon AJ, Kuo WH, Lin CW, Yang SF*. Role of ERCC5 polymorphism in risk of hepatocellular carcinoma. Oncology Letters 2011; 2: 911-914. (SCI)
7. Chien MH, Yeh KT, Li YC, Hsieh YH, Lin CH, Weng MS, Kuo WH*, Yang SF*. Effects of E-cadherin (CDH1) gene promoter polymorphisms on the risk and clinicopathological development of hepatocellular carcinoma. Journal of Surgical Oncology 2011; 104: 299-304. (SCI)
8. Chang HR, Chen PN, Yang SF, Sun YS, Wu SW, Hung TW, Lian JD, Chu SC*, Hsieh YS*. Silibinin inhibits the invasion and migration of renal carcinoma 786-O cells in vitro, inhibits the growth of xenografts in vivo and enhances chemosensitivity to 5-fluorouracil and paclitaxel. Molecular Carcinogenesis 2011; 50: 811-823. (SCI)
9. Kuo DY, Chen PN, Yang SF, Chu SC, Chen CH, Kuo MH, Yu CH, Hsieh YS*. Role of reactive oxygen species-related enzymes in neuropeptide y and proopiomelanocortin-mediated appetite control: a study using atypical protein kinase c knockdown. Antioxidants & Redox Signaling 2011; 15:2147-2159. (SCI)
10. Chang CC, Wang PH, Su PH, Lin DB, Yang SF, Ying TH, Hsieh YH*. Significant elevation of plasma Pentraxin 3 in patients with pelvic inflammatory disease. Clinical Chemistry and Laboratory Medicine 2011; 49: 1655-1660. (SCI)
11. Wang PH*, Ko JL, Yang SF, Lin LY. Implication of human nonmetastatic clone 23 type 1 and its downstream gene lipocalin 2 in metastasis and patient’s survival of cancer of uterine cervix. International Journal of Cancer 2011; 129: 2380-2389. (SCI)
12. Tsai JP, Yang SF, Wu SW, Hung TW, Tsai HC, Lian JD, Chang HR*.Glutathione S-transferase gene polymorphisms are not major risks for susceptibility to post-transplantation diabetes mellitus in Taiwan renal transplant recipients. Journal of Clinical Laboratory Analysis 2011; 25: 432-435. (SCI)
13. Su CK, Yeh KT, Yeh CB, Wang PH, Ho SC, Chou MC, Liu KC, Yang SF*, Yi YC*. Genetic polymorphism of the plasminogen activator inhibitor-1 is associated with an increased risk of endometrial cancer. Journal of Surgical Oncology 2011; 104: 755-759. (SCI)
14. Chien MH, Yeh CB, Li YC, Wei LH, Chang JH, Peng YT, Yang SF, Kuo WH*. Relationship of Interleukin-8 gene polymorphisms with hepatocellular carcinoma susceptibility and pathological development. Journal of Surgical Oncology 2011; 104: 798-803. (SCI)
15. Wong RH, Wei JC, Huang CH, Lee HS, Chiou SY, Lin SH, Cai YW, Hung PH, Wang MF, Yang SF*. Association of IL-12B genetic polymorphism with the susceptibility and disease severity of ankylosing spondylitis. Journal of Rheumatology 2012; 39: 135-140. (SCI)
16. Ying TH, Yang SF, Tsai SJ, Hsieh SC, Huang YC, Bau DT, Hsieh YH*. Fisetin induces apoptosis in human cervical cancer HeLa cells through ERK1/2-mediated activation of caspase-8-/caspase-3-dependent pathway. Archives of Toxicology 2012; 86: 263-273. (SCI)
17. Yeh CB, Hsieh MJ, Hsieh YH, Chien MH, Chiou HL*, Yang SF*. Antimetastatic effects of Norcantharidin on hepatocellular carcinoma by transcriptional inhibition of MMP-9 through modulation of NF-kB activity. PLoS ONE 2012; 7: e31055. (SCI)
18. Lee YT, Chen SC, Shyu LY, Lee MC, Wu TC, Tsao SM*, Yang SF*. Significant elevation of plasma cathepsin B and cystatin C in patients with community-acquired pneumonia. Clinica Chimica Acta 2012; 413: 630-635. (SCI)
19. Chien MH, Ying TH, Hsieh YS, Chang YC, Yeh CM, Ko JL, Lee WS, Chang JH, Yang SF*. Dioscorea nipponica Makino inhibits migration and invasion of human oral cancer HSC-3 cells by transcriptional inhibition of matrix metalloproteinase-2 through modulation of CREB and AP-1 Activity. Food and Chemical Toxicology 2012; 50: 558-566. (SCI)
20. Chien MH, Chou LS, Chung TT, Lin CH, Chou MY, Weng MS, Yang SF, Chen MK*. Effects of E-cadherin (CDH1) gene promoter polymorphisms on the risk and clinicopathological development of oral cancer. Head & Neck 2012; 34: 405-411. (SCI)
21. Chung TT, Yeh CB, Li YC, Su SC, Chien MH, Yang SF, Hsieh YH*. Effect of RECK gene polymorphisms on hepatocellular carcinoma susceptibility and clinicopathologic feature. PLoS ONE 2012; 7: e33517. (SCI)
22. Chiang TC, Shyu LY, Tsao TC, Chien MH, Tsao SM*, Lee YT*, Yang SF*. Elevated plasma matrix metalloproteinase-9 protein and its gene polymorphism in patients with community-acquired pneumonia. Clinical Chemistry and Laboratory Medicine 2012; 50: 449-454. (SCI)
23. Liu CM, Yeh CJ, Yu CC, Chou MY, Lin CH, Wei LH, Lin CW, Yang SF*, Chien MH*. Impact of Interleukin-8 gene polymorphisms and environmental factors on oral cancer susceptibility in Taiwan. Oral Diseases 2012; 18: 307-314. (SCI)
24. Chien MH, Hsin CH, Chou LS, Chung TT, Lin CH, Weng MS, Chou MY, Chen MK*, Yang SF*. Interleukin-23 receptor polymorphism as a risk factor for oral cancer susceptibility. Head & Neck 2012; 34: 551-556. (SCI)
25. Su PH, Yang SF, Yu JS, Chen SJ, Chen JY*. Study of leptin levels and gene polymorphisms in central precocious puberty patients. Pediatric Research 2012; 71: 361-367. (SCI)