Serafim  Papadimitriou

Leonid I. Nefyodov



Nefyodov Leonid Ivanovich is the Professor of Biochemistry, Department and Research Supervisor of Laboratory of Biochemistry of Biologically Active substances of Yanka Kupala State University of Grodno, Belarus. He is the Founder (1989) and head of the scientific direction and school "Biochemistry of amino acids and development of ways of their practical application as universal regulators of a metabolism and medicinal prophylactics". Under the scientific guide of professor Nefyodov more than 20 doctor's and candidate of sciences thesis are defended. Nefyodov Leonid Ivanovich has more than 450 publications, including 235 articles in the reviewed academic domestic and specialized foreign periodicals, 4 monographs and 5 books, organizer and the scientific editor of materials of 6 international symposiums on biochemistry. Nefyodov's development are awarded by the diplomas and medals St.Petersburg’s Industrial Exhibition, International Exhibition of "Bruxelles Eureka' 95", medal of A. Schweitzer "For merits in sci-ence area", elected the honorary member and D.h.c. number of the European academies. He Works at the Grodno State University of Yanka Kupala since 2000. Since 2001 – heard, professor department of biochemistry, heard and the research supervisor of Laboratory of Biochemistry of Biologically Active substances.The methodology of researches and development of school of sciences of L.Nefyodov in the field of creation of new effective domestic medicinal and preventive preparations is based on operation of regulatory action of physiological (endogenous) concentration of the free amino acids defining regularities of formation of a metabolic imbalance at various pathological states and diseases. Fundamental stages on the way of creative formation and development of school of sciences were the results, methodology and strategy of researches presented in Nefyodov's monograph "Taurine: pharmacology, biochemistry and medical application" (1999) and the first international "amino acid" congresses of the CIS countries led to Grodno of organizational congress (1996, 2001), and also development and production of the patented domestic medicines ("Taurine", "Leucine", "Tryptophane", "Tavamine").


Area of Interest

His area of interests include biochemical mechanisms of regulatory effects of amino acids, their derivatives and compositions, methodology of use of amino acids as universal regulators of a metabolism, medicines, components of treatment and prophylactic food, including development of solutions and specialized mixes of this class of substances.

top publication

[1] Nefyodov L. Taurine (biochemistry, pharmacology, medical application) Grodno RIPH. - 1999.- 145 p.
[2] Amino Acids And Their Derivatives (chemistry, biochemistry, pharmacology, medicine) /ed. L.Nefyodov // Proc of Internat. Symp; Grodno. – 1996. - 125 p.
[3] Nefyodov LI. et al. Amino acids and their derivatives in tumour tissue from patients with breast cancer treated with Ukrain. Part VI. Drugs Exp Clin Res. 1996;22(3-5):155-7.
[4] Nefyodov al. Amino acids and their derivatives in blood plasma of patients with breast cancer treated with Ukrain. Part V. Drugs Exp Clin Res. 1996;22(3-5):159-61.
[5] Nefyodov, L.I. Celowo ukierunkowana regulacja rownowagi metabolizmu aminokwasami /L.I.Nefyodov // Proc of XXXIV Zjazd Polskego Towarzystwa Biochemicznego. - Bialystok, 1998. - p. 270.
[6] Biological activity and transport of drugs / ed. L. Nefyodov // Proc of Internat. Symp.; Grodno. – 1999. – 189 p.
[7] VI Ordinary General Assembly Society of Biochemistry of Belarus / ed. L. Nefyodov // Proc of Internat. Symp;. Grodno. – 2000. – 225 p.
[8] Amino acids and their derivatives in biology and medicine / ed. L. Nefyodov // Proc of Internat. Symp;. – Grodno. – 2001. – 124 p.
[9] Nefyodov, L.I. Target - oriented regulation of metabolic equilibrium by amino acids and strategy of their application as drugs with directional effects /L.I. Nefyodov // XXXVII Zjazd Polskiego towarzystwa biochemicznego, Torun.- 10-14 IX 2001.- p.327
[10] Nefyodov, L.I. The results of biochemical research and development of nitrogen-containing compounds of natural origin: methodology of exploitation of biological properties as universal natural regulators of metabolism and drugs. -
[11] Glazev AA, Nefedov LI. Changes in amino acid patterns of blood plasma in tumor patients treated with anticancer drug NSC-631570: possible approaches to cancer diagnostics // Biomed Khim. 2008 May-Jun;54(3):289-300
[12] Glazev AA, Nefedov LI. Reduced glutathione interaction with thiophosphoric derivatives of alkaloids of Chelidonium majus L. in vitro // Biomed Khim. 2009 Jan-Feb;55(1):114-20.
[13] Nefyodov L.I. et al. Determination of level of the added Chelidonium majus L alkaloids in blood of oncological patients as a high-selective method of diagnosis of a cancer of in vitro. Laboratory diagnostics. Eastern Europe – 2012.-â„–1. - P.66 - 71.
[14] Nefyodov L.I. et al. Mechanisms of realization of metabolic and specific antitumor activity of new antineoplastic preparation deglutam. Laboratory diagnostics. Eastern Europe – 2012. - No. 2. - P. 36 - 41.
[15] Nefyodov L. Creation Pathogenetic the Determined Compositions of Amino Acids and their Derivatives for Practical Realization of the Regulating Effect of these Substances. J. Blood Disordes & Transfusion. - 2015, V.6, â„–3 php?aid=53369