A Retrospective Analysis of Outcome following Neuronavigation Guided Trans-Nasal, Trans-Sphenoidal Microscopic Excision of Pituitary Tumors: Study at Khoula Hospital of Cases Operated Between 2009 and 2017.
Munthir Al-ZabinAli M. Al-Mashani1, MunthirJ. M. Al-Zabin1*, Neeraj Salhotra1, Maimuna S N Al Saadi1, Azmat Ali1
Affiliation
1Department of Neurosurgery, Khoula Hospital, Sultanate of Oman, Muscat
2Department of Histopathology, Khoula Hospital, Sultanate of Oman, Muscat
Corresponding Author
Dr. Munthir Al-Zabin, MD, PhD, Sr. Specialist, Department of Neurosurgery, Khoula Hospital, Sultanate of Oman, Muscat; E-mail: munthir.alzabin@yahoo.com
Citation
Al-Zabin, M., et al. A Retrospective Analysis of Outcome Following Neuronavigation Guided Trans-Nasal, Trans-Sphenoidal Microscopic Excision of Pituitary Tumors: Study at Khoula Hospital of Cases Operated Between 2009 and 2017. (2018) Int J Neurol Brain Dis 5(1): 1- 5.
Copy rights
© 2018 Al-Zabin, M. This is an Open access article distributed under the terms of Creative Commons Attribution 4.0 International License.
Keywords
Abstract
This is a 7-year retrospective analysis with the primary objective of noting the incidence of pituitary tumor recurrence after transnasal trans-sphenoidal approach using neuronavigation and operating microscope under a single operating unit. The secondary objective was to identify the type of tumor with highest secretory over activity and operative complications. The follow up period ranged between one to seven years.
The result of this analysis of 67 patients indicates that the tumor size ranged between 5.7 X 5.7 mm to 49.5 X 35.5 mm. Headache was the commonest presenting symptom in 83.6% cases.The incidence of functioning adenomas in this series was 80.5% with prolactin being the dominant over secretory hormone in 53.7% cases. We noted an overall recurrence rate of 17.9%. The most important complication was a CSF leak noted in 11 patients (16.4%). CSF leak was fully cured in all patients by using a lumbar drainage catheter and/or placement of fat at the leakage site. There was only one mortality is this series.