Journal of Gynecology & Neonatal Biology
First trimester fetal biparietal diameter and head circumference in Chinese population
- 11Department of Fetal Medicine and Prenatal Diagnosis, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510150, China
- 22Obstetrics & Gynecology Institute of Guangzhou, Guangzhou,510150, China
- 33The Medical Centre for Critical Pregnant Women in Guangzhou, Guangzhou, 510150, China
- 44Key Laboratory for Major Obstetric Diseases of Guangdong Province, Guangzhou, 510150, China
- 55Key Laboratory of Reproduction and Genetics of Guangdong Province
- 66Department of Obstetrics and Gynaecology, The University of Hong Kong, Queen Mary Hospital, Hong Kong, China
- 77Prenatal Diagnosis Center, Guangzhou Maternal and Neonatal Hospital, Guangzhou, 510623, China
- 88Department of Community Medicine, Faculty of Medicine, The University of Hong Kong, Hong Kong, China
- 99Department of Biostatistics, Southern Medical University, Guangzhou, China
- 1010Hong Kong Prenatal Diagnosis Center, Hong Kong, China
- ##The two authors contribute equally to this work
Min CHEN, Department of Fetal Medicine and Prenatal Diagnosis, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510150, China, E-mail: firstname.lastname@example.org
Min, C., et al. First Trimester Fetal Biparietal Diameter And Head Circumference In Chinese Population. (2017) J Gynecol Neonatal Biol 3(1): 27-31.
© 2017 Min, C. This is an Open access article distributed under the terms of Creative Commons Attribution 4.0 International License.
KeywordsBiometry; First trimester; Ultrasound; Fetus; Biparietal diameter; Head circumference
Objectives: To establish the reference ranges for fetal biparietal diameter and head circumference obtained by transabdominal ultrasound examination in the first trimester in Chinese women.
Methods: In this prospective cross-sectional study, 1351 normal singleton fetuses were examined transabdominally by 2 experienced observers in the first trimester of pregnancy in which the CRL was between 55 and 84 mm. Measurements of Biparietal Diameter (BPD), head circumference (HC) were prospectively collected. Charts and predictive equations were constructed from data obtained.
Results: Measurements of BPD, HC were correlated with CRL. CRL-based predictive equations were calculated using polynomial least squares regression analysis. HC = 7.710583 1.387393 * CRL-0.0037807 * CRL², R² = 0.5735, P = 0.000. BPD = 6.855277 0.2389065 * CRL, R² = 0.5355, P = 0.000. CRL-specific biometric charts were constructed.
Conclusions: There was a general increase in fetal biparietal diameter and head circumference with CRL. Chinese fetal biometry might be of help in first-trimester ultrasound examination in the local population.