Affiliation

Obstetrics & Gynecology Department, University of Miami, Miller School of Medicine, Miami, USA

Corresponding Author

Jose Carugno, Obstetrics & Gynecology Department, University of Miami, Miller School of Medicine, Miami, USA; E-mail: jac209@med.miami.edu

Citation

Carugno, J. Genital Herpes Current Perspectives. (2017) Invest Dermatol Venereol Res 3(2): 120- 124.

Copy rights

© 2017 Carugno, J. This is an Open access article distributed under the terms of Creative Commons Attribution 4.0 International License.

Abstract

  Herpes Simplex Virus-2(HSV-2) is a leading cause of vulvar ulcer disease. It is a sexually transmitted infection with recurring manifestations throughout the lifetime of infected patients. Primary and recurrent infections result in lesions on the genital area. Immuno compromised patients are susceptible to additional systemic infections including chronic non-healing ulcers. Currently prescribed medications, mostly nucleoside analogs, only reduce the symptoms caused by an active infection, but do not eliminate the virus. Adequate clinical and laboratory diagnosis as well as effective treatment is the best clinical approach to treat this recurrent disease.
  Genital herpes in one of the most common, persistent and highly infectious sexually transmitted viral infection caused by HSV 1 or HSV 2. Chronic herpetic genital ulcerations have become more prevalent since the start of the HIV epidemic and the relationship between these two viruses is increasingly important. Recurrent vulvar ulceration is usually caused by Herpes Simplex Virus (HSV) type 2. Differential diagnosis in patients with chronic vulvar ulcerations includes erosive lichen planes, lichen sclerosis, mucous membrane pemphigoid, pemphigus and Behcet’s disease[1]. This review aims to optimize the diagnosis, treatment and prevention of this challenging clinical condition.