Journal of Stem Cell and Regenerative Biology
Liver Regeneration: Summary of Involved Cell Types
- 1Anatomy and Embryology Department, Faculty of Medicine, University of Mansoura, Egypt
- 2Internal Medicine Department, Faculty of Medicine, University of Mansoura, Egypt
- 3Head of Egyptian Liver Research Institute and Hospital (ELRIAH), Mansoura, Egypt
- #Authors contributed equally to this manuscript
Hussein Abdellatif, Anatomy and Embryology Department, University of Mansoura, Egypt, Tel: 2 01145919955; E-mail: Hussein.firstname.lastname@example.org
Abdellatif, H., and Shiha, G. Liver Regeneration: Summary of Involved Cell Types. (2017) J Stem Cell Regen Biol 3(1): 122- 125.
© 2017 Abdellatif, H. This is an Open access article distributed under the terms of Creative Commons Attribution 4.0 International License.
Keywordsliver regeneration; Progenitor cells; Hepatocytes; Non parenchymal; Epithelial progenitors
The liver has unique capacity to regulate its growth and mass. Healing process in the liver is characterized by the proliferation of all existing cell lines within the liver, including hepatocytes, hepatic progenitor cells, non parenchymal epithelial progenitors and small heptocyte like cells. Normally the liver exhibits a very low level of cell turnover, but when an abnormal hepatocyte loss occurs, a rapid regenerative response is elicited from all of these cell types in the liver. In this article, we review broadly the natural repair of the liver in response to injury.