Journal of Pediatrics and Palliative Care
- 1Division of Allergy Immunology, Department of Medicine, Nassau University Medical Center, New York
- 2Division of Pediatric, Department of Emergency Medicine, Nassau University Medical Center, New York
- 3Division of Adult Emergency Medicine, Department of Emergency Medicine, Nassau University Medical Center, New York
Marianne Frieri, Nassau University Medical Center, Department of Medicine, 2201 Hempstead Turnpike, East Meadow, New York, 11554; E-mail: email@example.com
Frieri, M., et al. Pediatric Sepsis. (2017) J Palliat Care Pediatr 2(1): 60-62.
© 2017 Frieri, M. This is an Open access article distributed under the terms of Creative Commons Attribution 4.0 International License.
KeywordsPediatric sepsis; Protein C deficiency; Neonatal sepsis; Innate: Immunity
The purpose of this article is to understand pediatric sepsis, activation of the innate immune system and a synergistic relationship between the loss of organ functions and sepsis pathophsiology. Many complex factors such as genetics, physical agents, mediators and effectors are involved in the development of organ failure both in sepsis in children and neonates. The patient’s immune surveillance could fail to eliminate the pathogens with a release with inappropriate activation. These topics are very important for pediatricians, immunologists, and neonatologists.