The Reliability of Blood Glucose Point-of-Care Testing (POCT) System in China Teaching Hospital
Feng-fei Li1#, Yan Cao2#, Bing-liLiu1#, Reng-na Yan1#, Hong-hongZhu1#, Wei Rong1, He-feng Diao1, Jie Lan1, Xue-mei Zheng3, Li Zhang4, Hai-yan Yang5, Bing Xia6, Hui Zhan7, Xiao-fei Su1, Jin-dan Wu1, Dan-Feng Zhang1, Shu-kui Wang8*#, Jian-hua Ma1*#
Affiliation
- 1Department of Endocrinology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China
- 2Department of quality management, Nanjing First Hospital, Nanjing Medical University, Nanjing, China
- 3Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China
- 4Department of General Surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, China
- 5Emergency Intensive Care Unit, Nanjing First Hospital, Nanjing Medical University, Nanjing, China
- 6Department of Orthopedics, Nanjing First Hospital, Nanjing Medical University, Nanjing, China
- 7Department of Neuropathy, Nanjing First Hospital, Nanjing Medical University, Nanjing, China
- 8Central Laboratory, Nanjing First Hospital, Nanjing Medical University, Nanjing, China
- #Authors Contributed equally to this article
Corresponding Author
Jian-hua Ma, M.D., PhD, Department of Endocrinology, Nanjing First Hospital, Nanjing Medical University, 32 Gongqingtuan Road, Nanjing, China, 210012, Tel: +862552887091, Fax: +862552887016; E-mail: majianhua196503@126.com
Shu-kui Wang, M.D, PhD, Central Laboratory, Nanjing First Hospital, Nanjing Medical University, 68 Changle Road, Nanjing 210006, Jiangsu, China, Tel: +862552271000, Fax: +862552271108; E-mail: shukwang@163.com
Citation
Jian-hua, M., et al. The Reliability of Blood Glucose Point-of-Care Testing (POCT) System in China Teaching Hospital. (2017) Int J Hematol Ther 3(2): 1- 4.
Copy rights
© 2017 Jian-hua, M. This is an Open access article distributed under the terms of Creative Commons Attribution 4.0 International License.
Keywords
Abstract
Background: To observe the reliability of blood glucose Point-of-Care Testing (POCT) system in teaching hospital in China.
Methods: This was a single center, sectional study. Between Jun and Aug 2015, a total of 353 inpatients were recruited from Nanjing First Hospital, China. After 10-hr fasting, the finger point blood glucose concentrations were measured with POCT system. Venous blood specimens were collected by investigators within 5 min after the finger point blood glucose concentrations were measured. The venous blood samples were then divided into two parts, with one part for blood glucose concentration measurement in central laboratory, the other one part was for hematocrit measurement. The precision of POCT results was evaluated by the International Organization for Standardization (ISO) revised ISO15197:2013. The clinical accuracy of POCT results were assessed by Parkes Error Grid.
Results: A total of 372 blood glucose concentrations delivered from POCT were compared with venous serum blood glucose levels measured by central laboratory system. The precision of the POCT was 76.3 %, with the 81.8 % in patients with blood glucose concentrations > 5.55 mmol/L and 75.6 % in subjects with blood glucose concentrations ≤ 5.55 mmol/L. In addition, the precision of results of POCT in patients with lower (male 40 L/L and female 37 L/L) and normal (male 40 - 50 L/L and female 37-45 L/L) hematocrit concentrations were 73.4 % and 79.4 %, respectively. The Parkes Error Grid data showed that the results from POCT, being 89.58 % values in Zone A, 10.4 1% values in Zone B, and 100 % values in Zone A+B.
Conclusions: In this study, our data provided the real world of the reliability of results delivered from POCT was unfulfilled the standard of ISO15197:2013 of accuracy limits criteria in one hospital setting in China.
