Affiliation

Department of Pharmacy, School of medical and allied sciences,Galgotias University, Yamuna Expressway, Plot No- 17A, Greater Noida, India

Corresponding Author

Dharmendra Kumar,Research Scholar, Galgotias University, Plot No.2, Sector 17-A, Yamuna Expressway, Greater Noida, Gautam Buddh Nagar,Uttar Pradesh, India; Phone No: +918512009949; E-mail: rvnimiet@gmail.com

Citation

Dharmendra Kumar., et al. Nanoparticulate System for Cancer Therapy: An Updated Review (2018) J Nanotechnol Material Sci 5(1): 51 -67.

Copy rights

© 2018 Dharmendra K. This is an Open access article distributed under the terms of Creative Commons Attribution 4.0 International License

Keywords

Nanoparticle; Pharmaceutical nanotechnology; Cancer therapy; Nano chemotherapy

Abstract

  Nowadays, pharmaceutical nanotechnology has been developed as the most emerging branch in the field of pharmacy. “Nanotechnology refers to the nanosize formulation. These nanoformulations may be used in treatment of various life-threading diseases like cancer. Due to the advantages of their nano size and shape, nanoformulations have been shown to be favorable drug delivery systems and may be useful for encapsulating and conjugating of drugs, enabling most precise tumor targeting and controlled release. Nanoparticle drug delivery system have several advantages such as enhanced intracellular infiltration, hydrophobic solubility, and drug circulation time and also reduce non-specific uptake and toxic effect for cancer therapy. A large number of Nanoparticle technologies have been developed for cancer treatment to improve the therapeutic efficacy and safety for anticancer drugs. In this paper, we review the most significant advancement in pharmaceutical nanotechnologies with methods of preparation and their use in drug delivery for cancer therapy.