biography
Martin Morad, Ph.D., is Professor of Regenerative Medicine and Cell Biology at the Medical University of South Carolina (MUSC) and the University of South Carolina (USC) and Professor of Bioengineering at Clemson University. He is the Director of the Cardiac Signaling Center and holds the BlueCross Blue Shield of South Carolina Endowed Chair in Cardiovascular Health, which includes a unique three-way faculty appointment at the USC, MUSC and Clemson University. Dr. Morad is an internationally recognized scientist in the field of cardiac electrophysiology and calcium signaling. He has pioneered many seminal findings and technologies in the fields of electrophysiology and Cardiac signaling. He has had over 300 original publications, 19 of which have appeared in Science and Nature, and has trained over 90 Graduate students and postdoctoral fellows, most of whom have leading academic positions in American, European, and Asian Universities. Dr. Morad’s career is marked by an incessant drive to formulate new physiological and molecular concepts based on innovative technology and experimental approaches unique to his lab. He has had a distinguished scientific career as professor of Physiology and Medicine at University of Pennsylvania, Professor and Chair at Georgetown University
Area of Interest
Dr. Morad current research is focused primarily on the pathophysiology of heart failure and cardiac arrhythmias using adult stem cell technology.
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1. MORAD M. Excitation-contraction as a possible site for the inotropic action of epinephrine in cardiac muscle. Doctoral Thesis. State University of New York, New York, 1965.
2. KAVALER F, and MORAD M. Paradoxical effects of epinephrine on excitation-contraction coupling in cardiac muscle. Cir. Res. 18:492-501, 1966.
3. DUDEL J, MORAD M, and RUDEL, R. Contractions of single crayfish muscle fibers induced by controlled changes of membrane potential. Pflugers Arch. Physiol. 299:38 51, 1968.
4. MORAD M, and TRAUTWEIN W. The effect of the duration of the action potential on contraction in the mammalian heart muscle. Pflugers Arch. Gen. Physiol. 299:66-82, 1968.
5. MORAD M. Contracture and catecholamines in mammalian myocardium. Science 166:505-506, 1969.
6. MORAD M, and ORKAND RK. Excitation-contraction coupling in frog ventricle: Evidence from voltage-clamp studies. J. Physiol. 219:167-189, 1971.
7. MORAD M, and ROLETT EL. Relaxing effects of catecholamines on mammalian heart. J. Physiol. 224:537-558, 1972.
8. MORAD M, and GOLDMAN YE. Excitation-contraction coupling in heart muscle: Membrane control of development of tension. Prog. Biophys. Mol. Biol. 27:257-313, 1973.
9. WEISS J, and MORAD M. Single cell layered heart: Electromechanical properties of the heart of Boltenia ovifera. Science 186:750-752, 1974.
10. GREENSPAN AM, and MORAD M. Electromechanical studies on the inotropic effects of acetylstrophanthidin in ventricular muscle. J. Physiol. 253:357-384, 1975.
11. CLEEMANN L, DILLON S, and MORAD M. The sarcomere length tension relation of the single cell layered heart of \"sea potato.\" MDIBL Bull. 16:8-13, 1976.
12. KLINE R, and MORAD M. Potassium efflux and accumulation in heart muscle. Evidence from K+ electrode experiments. Biophys J. 16:367-372, 1976.
13. CLEEMANN L, and MORAD M. Extracellular potassium accumulation and inward going potassium rectification in voltage clamped ventricular muscle. Science 191:90-92, 1976.
14. SALAMA G, and MORAD M. Merocyanine 540 as an optical probe of transmembrane electrical activity in the heart. Science 191:485-487, 1976.
15. MORAD M, and GOLDMAN Y. Clarification of membrane conductance measurements in ventricular heart muscle. J. Mol. Cell. Cardio. 8:169-172, 1976.
16. WEISS J, GOLDMAN Y, and MORAD M. Electromechanical properties of the single cell-layered heart of the tunicate Boltenia ovifera (sea potato). J. Gen. Physiol. 69:503-518, 1976.
17. GOLDMAN Y, and MORAD M. Measurement of transmembrane potential and current in cardiac muscle: A new voltage clamp method. J. Physiol. 268:613-654, 1977.
18. GOLDMAN Y, and MORAD M. Ionic membrane conductance during the time course of the cardiac action potential. J. Physiol. 288:655-695, 1977.
19. GOLDMAN Y, and MORAD M. Regenerative repolarization of the frog ventricular action potential: A time and voltage-dependent phenomenon. J. Physiol. 268:575-611, 1977.
20. KLINE R, and MORAD M. Potassium efflux in heart muscle during activity: Extracellular accumulation and its implications. J. Physiol. 280:537-558, 1978.
21. MORAD M, WEISS J, and CLEEMANN L. The inotropic action of adrenaline on cardiac muscle: Does it relax or potentiate tension. Eur. J. Cardiol., 7(suppl):53-62, 1978.
22. CLEEMANN L, and MORAD M. Extracellular potassium accumulation in voltage-clamped frog ventricular muscle. J. Physiol. 286:83-111, 1979.
23. CLEEMANN L, and MORAD M. Potassium currents in frog ventricular muscle: Evidence from voltage clamp currents and extracellular K accumulation. J. Physiol. 286:113-143, 1979.
24. MORAD M, and SALAMA G. Optical probes of membrane potential in heart muscle. J. Physiol. 292:267-295, 1979.
25. MAYLIE J, NUNZI MG, and MORAD M. Excitation-contraction coupling in ventricular muscle of dogfish (Squalus acanthias). MDIBL Bull. 19:84-87, 1979.