biography
IK-HYUN CHO is a Professor in Department of Convergence Medical Science and Anatomy, College of Oriental Medicine, Kyung Hee University, Seoul, Republic of Korea. He completed his Ph.D., Department of Veterinary Medicine, Konkuk University, Seoul, Republic of Korea.
Area of Interest
Neuroimmune diseases, Multiple sclerosis, Huntington’s and Parkinson’s disease, Excitotoxicity, Pain
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1. Choi JH, Lee MJ, Jang M, Kim EJ, Shim I, Kim HJ, Lee S, Lee SW, Kim YO, Cho IH. An Oriental Medicine, Hyungbangpaedok-San Attenuates Motor Paralysis in an Experimental Model of Multiple Sclerosis by Regulating the T Cell Response. PLoS One. 2015 Oct 7;10(10):e0138592. (IF, 3.234).
2. Lee SH, Kim SH, Noh YH, Choi BM, Noh GJ, Park WD, Kim EJ, Cho IH*, Bae CS*. Pharmacokinetics of Memantine after a Single and Multiple Dose of Oral and Patch Administration in Rats. Basic Clin Pharmacol Toxicol. 2015 Aug 27. doi: 10.1111/bcpt.12479. [Epub ahead of print]. (IF, 2.377). *Co-corresponding author.
3. Kim HJ, Shin EJ, Lee BH, Choi SH, Jung SW, Cho IH, Hwang SH, Kim JY, Han JS, Chung C, Jang CG, Rhim H, Kim HC, Nah SY. Oral Administration of Gintonin Attenuates Cholinergic Impairments by Scopolamine, Amyloid-β Protein, and Mouse Model of Alzheimer's Disease. Mol Cells. 2015 Sep 30;38(9):796-805. (IF, 2.090).
4. Jang M, Cho IH. Sulforaphane Ameliorates 3-Nitropropionic Acid-Induced Striatal Toxicity by Activating the Keap1-Nrf2-ARE Pathway and Inhibiting the MAPKs and NF-κB Pathways. Mol Neurobiol. 2015 Jun 23. In press. (IF, 5.137).
5. Lee MJ, Jang M, Choi J, Chang BS, Kim DY, Kim SH, Kwak YS, Oh S, Lee JH, Chang BJ, Nah SY, Cho IH. Korean Red Ginseng and Ginsenoside-Rb1/-Rg1 Alleviate Experimental Autoimmune Encephalomyelitis by Suppressing Th1 and Th17 Cells and Upregulating Regulatory T Cells. Mol Neurobiol. 2015 Apr 7. In press. (IF, 5.137).
6. Lee MJ, Jang M, Choi J, Chang BS, Kim DY, Kim SH, Kwak YS, Oh S, Lee JH, Chang BJ, Nah SY, Cho IH. Korean Red Ginseng and Ginsenoside-Rb1/-Rg1 Alleviate Experimental Autoimmune Encephalomyelitis by Suppressing Th1 and Th17 Cells and Upregulating Regulatory T Cells.Korean Red Ginseng and Ginsenoside-Rb1/-Rg1 Alleviate Experimental Autoimmune Encephalomyelitis by Suppressing Th1 and Th17 Cells and Upregulating Regulatory T Cells. Mol Neurobiol. 2015 Apr 7. In press. ( IF, 5.137).
7. Jung SW, Kim HJ, Lee BH, Choi SH, Kim HS, Choi YK, Kim JY, Kim ES, Hwang SH, Lim KY, Kim HC, Jang M, Park SK, Cho IH*, Nah SY*. Effects of Korean Red Ginseng extract on busulfan-induced dysfunction of the male reproductive system. J Ginseng Res. 2015 Jul;39(3):243-9. ( IF, 2.815). *Co-corresponding author.
8. Kim H, Lee BH, Choi SH, Kim HJ, Jung SW, Hwang SH, Rhim H, Kim HC, Cho IH, Nah SY. Gintonin stimulates gliotransmitter release in cortical primary astrocytes. Neurosci Lett. 2015 Jul 17;603:19-24. ( IF, 2.030).
9. Min H, Hong J, Cho IH, Jang YH, Lee H, Kim D, Yu SW, Lee S, Lee SJ. TLR2-induced astrocyte MMP9 activation compromises the blood brain barrier and exacerbates intracerebral hemorrhage in animal models. Mol Brain. 2015 Apr 10;8:23.( IF, 4.902).
10. Kim MH, Choi YY, Cho IH, Hong J, Kim SH, Yang WM. Angelica sinensis induces hair regrowth via the inhibition of apoptosis signaling. Am J Chin Med. 2014;42(4):1021-34. (IF, 2.775).
11. Jang M, Lee MJ, Cho IH. Ethyl pyruvate ameliorates 3-nitropropionic acid-induced striatal toxicity through anti-neuronal cell death and anti-inflammatory mechanisms. Brain Behav Immun. 2014 Feb 25. pii: S0889-1591(14)00016-6. (IF, 5.889).
12. Jang M, Lee MJ, Lee JM, Bae CS, Kim SH, Ryu JH, Cho IH. Oriental medicine Kyung-Ok-Ko prevents and alleviates dehydroepiandrosterone-induced polycystic ovarian syndrome in rats. PLoS One. 2014 Feb 10;9(2):e87623. (IF, 3.234).
13. Choi YY, Kim MH, Cho IH, Kim JH, Hong J, Lee TH, Yang WM. Inhibitory effect of Coptis chinensis on inflammation in LPS-induced endotoxemia. J Ethnopharmacol. 2013 Sep 16;149(2):506-12. (IF, 2.755).
14. Lee H, Lee S, Cho IH*, Lee SJ*. Toll-Like Receptors: Sensor Molecules for Detecting Damage to the Nervous System. Curr Protein Pept Sci. 2013. In press. (IF, 2.326). *Co-corresponding author.
15. Ahn G, Bing SJ, Kang SM, Lee WW, Lee SH, Matsuda H, Tanaka A, Cho IH, Jeon YJ, Jee Y. The JNK/NFkB pathway is required for the activation of murine lymphocytes induced by a sulfated polysaccharide isolated from Ecklonia cava. Biochim Biophys Acta. 2013;1830:2820–2829. (IF, 5.000).