biography
Scimeca Manuel, Biologist, (cellular and molecular Biology degree in 2008; Medical Biotecnology degree in 2011, PhD degree in 2015) student coordinator both Breast-â€Bone section of Anatomic Pathology laboratory, (University of Rome “Tor Vergata”) and Istology laboratory research (TMALab). PostDoc position in Italian Space Agency (ASI) “Multidisciplinary study of the effects of microgravity on bone cells” project. Ten scientific papers in international journal and 3 chapters in book published. Participation to the European group of breast pathology study.
Area of Interest
Breast microcalcifications
Bone-â€Muscle crosstalk
Bone age-â€related diseases
Transmission electron microscopy and Microanalysis
Nanoparticles and Nanotoxicity
Thyroid calcification
Melanoma diseases
top publication
Scimeca M, Pietroiusti A, Milano F, Anemona L, Orlandi A, Marsella LT, Bonanno A. Elemental analysis of histological specimens: a method to unmask nano asbestos fibers. European Journal of Histochemistry 2014; 2573. http://dx.doi.org/10.4081/ejh.2016.2573
Di Pietro G, Manenti G, Vinicola V, Fusco A, Baldi J, Scimeca M, Hagberg G, Bozzali M, Simonetti G, Tarantino U. Bone-marrow lipid profiles from peripheral skeleton as potential biomarkers for osteoporosis: a 1H-MR Spectroscopy study. Acad Radiol. 2016 Mar;23(3):273-83.
Scimeca M, Antonacci C, Bonanno E. Breast Microcalcifications: A Focus. J Cell Sci Ther 2015, S8.
Scimeca M, Antonacci C, Colombo D, Bonfiglio R, Buonomo OC, Bonanno E. Emerging prognostic markers related to mesenchymal characteristics of poorly differentiated breast cancers. Tumour Biol. 2015 Nov 12.
Gambacurta A, Carpentieri A, Cozzoli E, Scimeca M, Bonanno E, and Sardanelli AM. Differentiation of human neuroblastoma cells towards the osteogenic lineage by mTor inhibitor. Cell Death Dis.2015 Nov 12;6:e1974
Tarantino U, Scimeca M, Piccirilli E, Tancredi V, Baldi J, Gasbarra E, Bonanno E. Sarcopenia: a histological and immunohistochemical study on age-related muscle impairment. Aging Clin ExpRes. 2015 Jul 22.
Scimeca M, Bonanno E, Piccirilli E, Baldi J, Mauriello A, Orlandi A, Tancredi V, Gasbarra E, Tarantino U. Satellite Cells CD44 Positive Drive Muscle Regeneration in Osteoarthritis Patients.Stem Cells Int. 2015;2015:469459.
Graziani G, Artuso S, De Luca A, Muzi A, Rotili D, Scimeca M, Atzori MG, Ceci C, Mai A, Leonetti C,Levati L, Bonanno E, Tentori L, Caccuri AM. A new water soluble MAPK activator exertsantitumor activity in melanoma cells resistant to the BRAF inhibitor vemurafenib. BiochemPharmacol. 2015 May 1;95(1):16-27.
De Luca A, Rotili D, Carpanese D, Lenoci A, Calderan L, Scimeca M, Mai A, Bonanno E, Rosato A,Geroni C, Quintieri L, Caccuri AM. A novel orally active water-soluble inhibitor of humanglutathione transferase exerts a potent and selective antitumor activity against human melanoma xenografts. Oncotarget. 2014 Dec 18.
Scimeca M, Orlandi A, Terrenato I, Bischetti S, Bonanno. Assessment of metal contaminants in non-small cell lung cancer by EDX microanalysis. European Journal of Histochemistry 2014;volume 58:2403
Di Marco G, Gismondi A, Canuti L, Scimeca M, Volpe A, Canini A. Tetracycline accumulates in Iberis sempervirens L. through apoplastic transport inducing oxidative stress and growth inhibition. PLANT BIOLOGY, vol. 14; p. 286-286, ISSN: 1438-8677, doi: 10.1111/plb.12102
Scimeca M., Giannini E, Antonacci C, Pistolese CA, Spagnoli LG, Bonanno E (2014). Microcalcifications in breast cancer: an active phenomenon mediated by epithelial cells with mesenchymal characteristics. BMC CANCER, vol. 14; p. 286-286, ISSN: 1471-2407, doi: 10.1186/1471-2407-14-286.
Scimeca M., Anemona A, Colantoni A, Bonanno E (2013). Ultrastructural and Microanalytical Study of a Subcutaneous Granuloma HPV Tetravalent Vaccine Induced: A Case Report and Review of Literature. JOURNAL OF MEDICAL CASES, vol. 14; p. 286-286, ISSN: 1923-4155, doi:10.4021/jmc1193w.
Chapter in Book
Luigi Giusto Spagnoli, Alessandro Mauriello, Augusto Orlandi, Manuel Scimeca, Antonio Volpe,and Elena Bonanno. Aging. MUSCLE Fundamental Biology and Mechanisms of Disease. vol. II, p.2012 1371-1382.
Scimeca M, Piccirilli E, Gasbarra E, Bonanno E and Tarantino U. Bone Metabolism and Bone Healing. Bone healing: an update. Benazzo, Mosconi (Eds.). 2015 (in press)