biography
Dr. Andrey A Zamyatnin obtained his Graduation and then received his PhD from the Department of Virology, Biological Faculty, Lomonosov Moscow State University, Moscow, Russia. He then pursued his Postdoc from the Department of Plant Biology and Forest Genetics, Swedish University of Agricultural Sciences, Uppsala, Sweden. He also worked as an Assistant Professor in the Department of Plant Biology and Forest Genetics, Swedish University of Agricultural Sciences, Uppsala, Sweden. He also served as Vice Head for Innovative Development of the Institute of Molecular Medicine, Sechenov First Moscow State Medical University, Moscow, Russia. Currently he is the Head of the Institute of Molecular Medicine, Sechenov First Moscow State Medical University, Russia.
Area of Interest
Programmed cell death; Protein processing; Intracellular communications; Virus-cell interactions; Regulation of gene expression; RNAi; Oxidative stress; Aging; Neurodegeneration; Ophthalmology; Cancer; Regenerative medicine; Personalized medicine; Molecular markers; Biotechnology; Drug design; Novel drug candidates
top publication
1. * Golovastova MO, Tsoy LV, Bocharnikova AV, Korolev DO, Gancharova OS, Alekseeva EA, Kuznetsova EB, Savvateeva LV, Skorikova EE, Strelnikov VV, Varshavsky VA, Vinarov AZ, Nikolenko VN, Glybochko PV, Zernii EY, Zamyatnin AA, Bazhin AV, Philippov PP The cancer-retina antigen recoverin as a potential biomarker for renal tumors. TUMOR BIOLOGY in press 2016
2. * Savvateeva LV, Zamyatnin AA Prospects of Developing Medicinal Therapeutic Strategies and Pharmaceutical Design for Effective Gluten Intolerance Treatment. CURRENT PHARMACEUTICAL DESIGHN Volume: 22 Issue: 16 Pages: 2439-2449 2016
3. Zernii EY, Baksheeva VE, Iomdina EN, Averina OA, Permyakov SE, Philippov PP, Zamyatnin AA, Senin II Rabbit models of ocular diseases: new relevance for classical approaches. CNS & NEUROLOGICAL DISORDERS - DRUG TARGETS Volume: 15 Issue: 3 Pages: 267-291 2016
4. * Zamyatnin AA Plant Proteases Involved in Regulated Cell Death. BIOCHEMISTRY-MOSCOW Volume: 80 Issue: 13 Pages: 1701-1715 Published: APR 2015
5. * Savvateeva LV, Schwartz AM, Gorshkova LB, Gorokhovets NV, Makarov VA, Reddy VP, Aliev G, Zamyatnin AA Prophylactic admission of an in vitro reconstructed complexes of human recombinant heat shock proteins and melanoma antigenic peptides activates anti-melanoma responses in mice. CURRENT MOLECULAR MEDICINE Volume: 15 Issue: 5 Pages: 462- 468 Published: 2015
6. * Savvateeva LV, Gorokhovets NV, Makarov VA, Serebryakova MV, Solovyev AG, Morozov SY, Reddy VP, Zernii EY, Zamyatnin AA, Aliev G Glutenase and collagenase activities of wheat cysteine protease Triticain-α: Feasibility for enzymatic therapy assays. THE INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY Volume: 62 Pages: 115-124 Published: MAY 2015
7. * Rudchenko MN, Zamyatnin AA Prospects for Using Self-Assembled Nucleic Acid Structures. BIOCHEMISTRY-MOSCOW Volume: 80 Issue: 4 Pages: 391-399 Published: APR 2015
8. Baksheeva VE, Nazipova AA, Zinchenko DV, Serebryakova MV, Senin II, Permyakov SE, Philippov PP, Li Y, Zamyatnin AA, Zernii EY, Aliev G Ca2+-myristoyl switch in neuronal calcium sensor-1: a role of C-terminal segment. CNS & NEUROLOGICAL DISORDERS - DRUG TARGETS Volume: 14 Issue: 4 Pages: 437- 451 Published: 2015
9. Iomdina EN, Khoroshilova-Maslova IP, Robustova OV, Averina OA, Kovaleva NA, Reddy VP, Aliev G, Zamyatnin AA, Skulachev MV, Senin II, Skulachev VP Mitochondria-targeted antioxidant SkQ1 reverses glaucomatous lesions in rabbits. FRONTIERS IN BIOSCIENCE-LANDMARK Volume: 20 Issue: 5 Pages: 892-901 Published: JAN 2015
10. Herrera AS, Del C A Esparza M, Md Ashraf G, Zamyatnin AA, Aliev G Beyond Mitochondria, What would be the Energy Source of the Cell? CENTRAL NERVOUS SYSTEM AGENTS IN MEDICINAL CHEMISTRY Volume: 15 Issue: 1 Pages: 32-41 Published: 2015
11. Aliev G, Priyadarshini M, Reddy VP, Grieg NH, Kaminsky Y, Cacabelos R, Ashraf GM, Jabir NR, Kamal MA, Nikolenko VN, Zamyatnin AA, Benberin VV, Bachurin SO Oxidative Stress Mediated Mitochondrial and Vascular Lesions as Markers in the Pathogenesis of Alzheimer Disease. CURRENT MEDICINAL CHEMISTRY Volume: 21 Issue: 19 Pages: 2208-2217 Published: JUN 2014
12. Gancharova OS, Manskikh VN, Zamyatnin AA, Philippov PP Organotypic culture of neural retina as a research model of neurodegeneration of ganglion cells. BIOCHEMISTRY-MOSCOW Volume: 78 Issue: 11 Pages: 1280-1286 Published: NOV 2013
13. Aliev G, Solís-Herrera A, Yi L, Kaminsky YG, Yakhno NN, Nikolenko VN, Zamyatnin AA, Benberin VV, Bachurin SO Human photosynthesis, the ultimate answer to the long term mystery of Kleiber's law or E = M3/4: Implication in the context of gerontology and neurodegenerative diseases. OPEN JOURNAL OF PSYCHIATRY Volume: 3 Issue: 4, Pages: 408-421. Published: OCT 2013
14. * Solovieva AD, Frolova OY, Solovyev AG, Morozov SY, Zamyatnin AA Effect of mitochondria-targeted antioxidant SkQ1 on programmed cell death induced by viral proteins in tobacco plants. BIOCHEMISTRY-MOSCOW Volume: 78 Issue: 9 Pages: 1006-1012 Published: SEP 2013
15. * Bogdanov AA, Zinovkin RA, Zamyatnin AA RNA editing: breaking the dogma. BIOCHEMISTRY-MOSCOW Volume: 76 Issue: 8 Pages: 867-868 Published: AUG 2011
16. Skulachev MV, Antonenko YN, Anisimov VN, Chernyak BV, Cherepanov DA, Chistyakov VA, Egorov MV, Kolosova NG, Korshunova GA, Lyamzaev KG, Plotnikov EY, Roginsky VA, Savchenko AY, Severina II, Severin FF, Shkurat TP, Tashlitsky VN, Shidlovsky KM, Vyssokikh MY, Zamyatnin AA, Zorov DB, Skulachev VP Mitochondrial-Targeted Plastoquinone Derivatives. Effect on Senescence and Acute Age-Related Pathologies. CURRENT DRUG TARGETS Volume: 12 Issue: 6 Pages: 800-826 Published: JUN 2011
17. * Zamyatnin AA, Lyamzaev KG, Zinovkin RA A-to-I RNA Editing: A Contribution to Diversity of the Transcriptome and an Organism's Development. BIOCHEMISTRY-MOSCOW Volume: 75 Issue: 11 Pages: 1316-1323 Published: NOV 2010
18. Sundstrom JF, Vaculova A, Smertenko AP, Savenkov EI, Golovko A, Minina E, Tiwari BS, Rodriguez-Nieto S, Zamyatnin AA, Valineva T, Saarikettu J, Frilander MJ, Suarez MF, Zavialov A, Stahl U, Hussey PJ, Silvennoinen O, Sundberg E, Zhivotovsky B, Bozhkov PV Tudor staphylococcal nuclease is an evolutionarily conserved component of the programmed cell death degradome. NATURE CELL BIOLOGY Volume: 11 Issue: 11 Pages: 1347-U198 Published: NOV 2009
19. Antonenko YN, Avetisyan AV, Bakeeva LE, Chernyak BV, Chertkov VA, Domnina LV, Ivanova OY, Izyumov DS, Khailova LS, Klishin SS, Korshunova GA, Lyamzaev KG, Muntyan MS, Nepryakhina OK, Pashkovskaya AA, Pletjushkina OY, Pustovidko AV, Roginsky VA, Rokitskaya TI, Ruuge EK, Saprunova VB, Severina II, Simonyan RA, Skulachev IV, Skulachev MV, Sumbatyan NV, Sviryaeva IV, Tashlitsky VN, Vassiliev JM, Vyssokikh MY, Yaguzhinsky LS, Zamyatnin AA, Skulachev VP Mitochondria-targeted plastoquinone derivatives as tools to interrupt execution of the aging program. 1. Cationic plastoquinone derivatives: Synthesis and in vitro studies. BIOCHEMISTRY-MOSCOW Volume: 73 Issue: 12 Pages: 1273-1287 Published: DEC 2008
20. * Zamyatnin AA, Solovyev AG, Bozhkov PV, Valkonen JPT, Morozov SY, Savenkov EI Assessment of the integral membrane protein topology in living cells. PLANT JOURNAL Volume: 46 Issue: 1 Pages: 145-154 Published: APR 2006
21. Bozhkov PV, Suarez MF, Filonova LH, Daniel G, Zamyatnin AA, Rodriguez-Nieto S, Zhivotovsky B, Smertenko A Cysteine protease mcll-Pa executes programmed cell death during plant embryogenesis. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA Volume: 102 Issue: 40 Pages: 14463-14468 Published: OCT 4 2005
22. Lukhovitskaya NI, Yelina NE, Zamyatnin AA, Schepetilnikov MV, Solovyev AG, Sandgren M, Morozov SY, Valkonen JPT, Savenkov EI Expression, localization and effects on virulence of the cysteine-rich 8 kDa protein of Potato mop-top virus. JOURNAL OF GENERAL VIROLOGY Volume: 86 Pages: 2879-2889 Part: Part 10 Published: OCT 2005