Alessandra Bertoli



Alessandra Bertoli is a permanent researcher at the University of Pisa-Department of Pharmacy. Educational Background: Master Degree (II level) on “The Quality System in the analytical chemistry laboratory” (University of Parma, 2005); Post Doctoral Position at the Department of Pharmaceutical Sciences-Faculty of Pharmacy (University of Calabria, 1999-2003); PhD Degree on Science and Tecnology in Medicinal Plants (University of Pisa, 1995-1998); Degree in Pharmaceutical Chemistry and Technologies (University of Pisa, 1993). Co-coordination of experimental and dissemination activities of National and International Research Projects. Teaching activity: "System and quality control of MAPs and derivatives" (Department of Pharmacy, University of Pisa); “Phytochemistry and Quality control of medicinal plants and their derivatives” (Department of Pharmacy, University of Pisa); “Phytochemistry” (Faculty of Pharmacy, University of Calabria, 1998); Invited lecturer in International Congresses and in undergraduated and post-graduated University courses.She has many publications in international scientific journals with high impact factor.


Area of Interest

1.Monitoring volatile and non-volatile plant constituents in medicinal.
2.Aromatic and food plants derived from wild collection.
3.Agronomic or biotechnological production.
4.Development of validated methods for the standardization of valuable raw plant material (collection and post-harvested quality).
5.Promotion of the legislative and technical role of harmonization processes in modern phytotherapy and nutritional programmes.

top publication

1. Ruffoni, B; Bertoli, A; Pistelli, L; Pistelli, L, Micropropagation of Salvia wagneriana Polak and hairy root cultures with rosmarinic acid production Natural Product Research, 2016, 4, 1-7.

2. Chiara Giacomelli, Letizia Natali, Maria Letizia Trincavelli, Simona Daniele, Alessandra Bertoli, Guido Flamini, Alessandra Braca, Claudia MartiniNew insights into the anticancer activity of carnosol: p53 reactivation in the U87MG human glioblastoma cell line, The International Journal of Biochemistry & Cell Biology, 74, 2016, 95–108.

3. Alessandra Bertoli, Maria Cecilia Loi, Cecilia Noccioli, Lucia Maxia, Anna- Camilla Moonen, Luisa Pistelli, Volatile constituents as complementary tools to characterize seven Sardinian Genista species, Biochemical Systematics and Ecology, 2015, http//

4. Bertoli Alessandra, Cuneyt Cirak, Fatih Lseyis, H. origanifolium Willd: the essential oil composition of a new valuable species. Industrial Crops and Products, 2015, http//

5. Noccioli C., Bertoli A., Agus E., De Logu A., Pistelli L., HPLC-DAD-MS analysis and antiviral activity of different extracts and isolated constituents from Bituminaria bituminosa, Chemistry of Natural Compounds, 4, 726 -729, 2014.

6. Olga Russina, Ruggero Caminiti, Alessandro Triolo, Sunita Rajamani, Bernardo Melai, Alessandra Bertoli, Cinzia Chiappe, Physico-chemical properties and nanoscale morphology in N-alkyl-N-methylmorpholinium dicyanamide room temperature ionic liquids, Journal of Molecular Liquids, vol. 187, p. 252-259, 2013.

7. Cuneyt Cirak, Alessandra Bertoli, Aromatic profiling of wild and rare species growing in Turkey: Hypericum aviculariifolium Jaub. and Spach subsp. depilatum (Freyn and Bornm.) Robson var. depilatum and Hypericum pruinatum Boiss. and Bal.. Natural Product Research, vol. 27, p. 100-107, 2013.

8. A. Bertoli, M. Lucchesini, A. Mensuali-Sodi, M. Leonardi, S. Doveri, A. Magnabosco, L. Pistelli, 2013. Aroma characterization and UV elicitation of purple basil from different plant tissue cultures, Food Chemistry, vol. 141, p. 776-787.

9. Cuneyt Cirak, Alessandra Bertoli, Aromatic profiling of wild and rare species growing in Turkey: Hypericum aviculariifolium Jaub. and Spach subsp. depilatum (Freyn and Bornm.) Robson var. depilatum and Hypericum pruinatum Boiss. and Bal. Nat Prod Res, 27, 100-107, 2012.

10. S. Sárosi, J. Bernáth A. Bertoli, L. Pistelli, S. Benvenuti, Essential Oil Polymorphism of Thymus pulegioides Collected in Monti Pisani (Italy), Acta Hort. 955, 59-64, 2012.

11. C. Noccioli, L. Luciardi, S. Barsellini, C. Favro, A. Bertoli, A. Bader, M.C. Loi, and L. Pistelli, Flavonoids from two Italian Genista species: Genista cilentina and Genista sulcitana Chemistry of Natural Compounds, 48, 672-673, 2012.

12. Bertoli Alessandra, Leonardi Michele, Krzyzanowska Justina, Wieslaw Oleszek, Pistelli Luisa, Mentha longifolia in vitro cultures as safe source of flavouring Ingredients, Acta Biochimica Polonica, 58, 581-587, 2011.

13. Cuneyt Cirak, Bertoli Alessandra, Pistelli Luisa, Fatih Lseyis, Essential oil composition and variability of Hypericum perforatum from wild populations of northern Turkey, Pharmaceutical Biology, 48, 906-911, 2010.

14. Pistelli Laura, Bertoli Alessandra, Gelli Federica, Bedini Laura, Ruffoni Barbara, Pistelli Luisa, Production of Curcuminoids in Different in vitro Organs of Curcuma longa, Natural Product Communications, 7, 1-6, 2012.

15. Pistelli Luisa, Mancianti Francesca, Bertoli Alessandra, Cioni Pier luigi, Leonardi Michele, Pisseri Francesca, Mugnaini Linda, Nardoni Simona, Antimycotic Activity of Some Aromatic Plants Essential Oils Against Canine Isolates of Malassezia pachydermatis: An in vitro Assay, The Open Mycology Journal, 6, 17-21, 2012.

16. Bertoli A., Conti B., Mazzoni V., Meini L., Pistelli L. Volatile chemical composition and bioactivity of six essential oils against the stored food insect Sitophilus zeamais Motsch. (Coleoptera Dryophthoridae) (2012) Natural Product Research, 26 (22), pp. 2063-2071.

17. Bertoli Alessandra, Cirak C., Leonardi Michele, Seyis F., Pistelli Luisa, Morphogenetic changes in essential oil composition of Hypericum perforatum during the course of ontogenesis, Pharmaceutical Biology, 49/7, 741-751, 2011.

18. Bertoli Alessandra, Fambrini Marco, Doveri Silvia, Leonardi Michele, Pugliesi Claudio, Pistelli Luisa, Pollen Aroma Fingerprinting of two Sunflower (Helianthus annuus L.) Genotype Characterized by Different Pollen Colors, Chemistry & Biodiversity, 8/9, 1766-1775, 2011.

19. Rea G, Antonacci A., Lambreva M., Pastorellin S., Tibuzzi Anna, Ferrari S., Fischer D., Johanningmeier U., Oleszek Wieslaw, Doroszewska T., Rizzo Am, Berselli Pvr, Berra B., Bertoli Alessandra, Pistelli Luisa, Ruffoni B., Calasblanchard C., Marty Jl, Litescu Sc, Diaconu M., Touloupakis E, Ghanotakis D., Giardi Mt, Integrated Plant Biotechnologies Applied To Safer And Healthier Food Production: The Nutra-Snack Manufacturing Chain, Trends in Food Science & Technology, 22, 353-366, 2011.

20. Nardoni Simona, Bertoli Alessandra, Pinto L, Mancianti Francesca, Pisseri F, Pistelli Luisa, In vitro effectiveness of tea tree oil against Trichophyton equinum, Journal de Mycologie Medicale, 20, 75-79, 2010.

21. Ruffoni Barbara, Pistelli Laura, Bertoli Alessandra, Pistelli Luisa, Plant cell cultures: bioreactors for industrial production, Advances in Experimental Medicine and Biology, 698, 203-220, 2010.

22. Pistelli Laura, Giovannini Annalisa, Ruffoni Barbara, Bertoli Alessandra, Pistelli Luisa, Hairy Root Cultures for Secondary Metabolites Production, Advances in Experimental Medicine and Biology, 698,167-185, 2010.

23. Bertoli Alessandra, Ruffoni Barbara, Pistelli Laura, Pistelli Luisa, Analytical methods for the extraction and identification of secondary metabolite production in 'in vitro' plant cell cultures, Advances in Experimental Medicine and Biology, 698, 1-17, 2010.

24. Conti Barbara, Canale Angelo, Bertoli Alessandra, Gozzini Francesca, Pistelli Luisa, Essential oil composition and larvicidal activity of six Mediterranean aromatic plants against the mosquito Aedes albopictus (Diptera: Culicidae)., Parasitology Research,107, 1455-1461, 2010.

25. Bertoli Alessandra, Ciccarelli Daniela, Garbari Fabio, Pistelli Luisa, Flavonoids isolated from Medicago littoralis Rhode (Fabaceae): their ecological and chemosystematic significance, Caryologia, 63, 106-114, 2010.