Divakar Sharma



Dr. Divakar Sharma PhD. is a Biotechnologist recognized in the field of Microbial Proteome research particularly for Tuberculosis and other diseases especially in Drug resistance and Drug induced studies. Dr. Sharma has studied at many universities and holds multiple degrees including a Master of science degree in Biotechnology from the C.S.J.M. University India and a PhD in Biotechnology from the Jiwaji University India. He is distinguished as one of the best researchers in the field of microbial proteomics. Dr. Sharma research has high clinical relevance that will lead to the development of Diagnostics, therapeutics and vaccines against drug resistant tuberculosis and other diseases and biomarkers as predictive correlate of infection. Dr. Sharma has author of a number of research articles in journals of international repute and serves as peer reviewer for several journals. "Dr. Sharma is currently involved in the ICMR Funded project "Secretome analysis of aminoglycosides resistant M.tuberculosis clinical isolates by Proteomic approach"


Area of Interest

Molecular Biology & Microbiology

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1. Sharma, D., Lata, M., Faheem, M., Khan,AU., Joshi, B., Venkatesan, K., Shukla, S. and Bisht, D. M.tuberculosis ferritin (Rv3841): Potential involvement in Amikacin (AK) & Kanamycin (KM) resistance. (BBRC-Accepted)
2. Sharma, D. and Bisht, D. (2016) An efficient and rapid method for enrichment of lipophilic proteins extraction from Mycobacterium tuberculosis H37Rv for two dimensional gel electrophoresis. Electrophoresis 37, 1187-1190.
3. Qayyum, S., Sharma, D., Bisht, D. and Khan AU*. (2016) Protein translation machinery holds a key for transition of planktonic cells to biofilm state in Enterococcus faecalis: A proteomic approach. BBRC 474, 652-659.
4. Refaya, A.K., Sharma, D., Kumar, V., Bisht, D., Narayanan, S. (2016) A Serine/threonine Kinase PknL, is involved in the adaptive response of Mycobacterium tuberculosis. Microbiological Research 190, 1-11.
5. Singhal, N., Kumar, M., Sharma, D., and Bisht, D. (2016) Protein profiling of intraphagosomal expressed proteins of Mycobacterium bovis BCG. Protein Pept Lett., 23(1): 51-54.
6. Sharma, D., Kumar, B., Lata, M., Joshi, B., Venkatesan, K., Shukla, S., and Bisht, D. (2015) Comparative proteomic analysis of aminoglycosides resistant and susceptible Mycobacterium tuberculosis clinical isolates for exploring potential drug targets. PLoS ONE 10(10): e0139414.
7. Sharma, D., Lata, M., Faheem, M., Khan, AU., Joshi, B., Venkatesan, K., Shukla, S., and Bisht, D. (2015) Cloning, expression and correlation of Rv0148 to amikacin & kanamycin resistance. Current Proteomics 12(2):96-100.
8. Lata, M*., Sharma, D*., Deo, N., Tiwari, PK., Bisht, D. and Venkatesan, K. (2015) Proteomic analysis of ofloxacin-mono resistant Mycobacterium tuberculosis isolates Journal of Proteomics 127, Part A,: 114-121. *Both authors contribute equally in this paper.
9. Lata, M., Sharma, D., Kumar, B., Deo, N., Tiwari, PK., Bisht, D. and Venkatesan, K. (2015) Proteome analysis of ofloxacin and moxifloxacin induced Mycobacterium tuberculosis isolates by proteomic approach. Protein Pept Lett. 22(4):362-371.
10. Sharma D.,* Shankar H., Lata M., Joshi B., Venkatesan K., & Bisht D. (2014) Culture filtrate proteome analysis of aminoglycoside resistant clinical isolates of Mycobacterium tuberculosis. Proceedings, BMC Infectious Diseases, 14(Suppl.):P60 doi:10.1186/1471-2334-14-S3-P60.
(IF-2.61) 11. Kumar, B., Sharma, D., Sharma, P., Katoch, V.M., Venkatesan, K. and Bisht, D. (2013) Proteomic analysis of Mycobacterium tuberculosis isolates resistant to kanamycin and amikacin. Journal of Proteomics 94: 68-77.