Nancy A. Monteiro-Riviere



Dr. Nancy A. Monteiro-Riviere, is a Regents Distinguished Research Scholar and University Distinguished Professor of Toxicology and Director, of the new Nanotechnology Innovation Center of Kansas State (NICKS).  She was a Professor of Investigative Dermatology and Toxicology at the Center for Chemical Toxicology Research and Pharmacokinetics, North Carolina State University (NCSU) for 28 years. She is also a Professor in the Joint Department of Biomedical Engineering at UNC-Chapel Hill/NCSU and Research Adjunct Professor of Dermatology, at UNC- Chapel Hill School of Medicine. She has a B.S. (cum laude) in Biology from Stonehill College, North Easton, MA and M.S. and Ph.D. in Anatomy and Cell Biology from Purdue University, West Lafayette, IN and completed a postdoctoral fellowship in toxicology at Chemical Industry Institute of Toxicology in Research Triangle Park, NC.  She was past-President of both the Dermal Toxicology and In Vitro Toxicology Specialty Sections of the National Society of Toxicology.  Dr. Monteiro-Riviere is a Fellow in The Academy of Toxicological Sciences, and in the American College of Toxicology.  She was the recipient of the Purdue University inaugural Distinguished Women Scholars Award, Kansas State University Woman of Distinction, and elected to attend the National Academy of Sciences special Keck Futures Initiative Conference on “Designing Nanostructures at the Interface Between Biomedical and Physical Systems”. She serves as Associate Editor for Wires Nanomedicine and Nanobiotechnology and for Materials Science and Engineering C: Materials for Biological Applications; and serves on the Editorial Boards of Nanomedicine, Nanotoxicology, Journal of Applied Toxicology, Cutaneous and Ocular Toxicology, Research and Reports in Transdermal Drug Delivery, and Toxicology in Vitro. She has served on several national and international expert review panels, including many in nanotoxicology, such as the National Research Council of the National Academies to Review the Federal Strategy to Address Environmental, Health, and Safety Research Needs for Engineered Nanoscale Materials and the International Council on Nanotechnology.  She has served as an invited expert for the National Nanotechnology Initiative on Nanomaterials.   She has given more than 145 invited presentations and published over 280 manuscripts in the field of skin toxicology and nanotoxicology and is Editor of the books “Nanotoxicology: Characterization and Dosing and Health Effects” and “Toxicology of the Skin - Target Organ Series” and “Nanotoxicology: Progress toward Nanomedicine”.


Area of Interest

1) Understanding the biological interactions and variables that can influence the interactions of nanomaterials in cells and tissues, as well as determine the physicochemical parameters that will affect their toxicity, absorption and penetration into skin or cells
2) Cellular uptake studies with biochemical inhibitors have identified the mechanisms of cellular uptake with some nanoparticles so that proper strategies can be developed to target nanomaterials to cancer cells
3) Nanomaterials are used in a variety of consumer products and cosmetics
4) We have shown that the physicochemical properties such as surface coatings and conjugations play a major role in penetration through skin and for cellular uptake
5) Studies have been conducted in skin in both in vivo and in vitro models to assess the absorption, penetration and toxicity of several different nanoparticles, chemicals, and novel pharmaceutical drug delivery devices

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