Dongzhi Wei




Area of Interest

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1. Hualei Wang, Wenyuan Gao, Huihui Sun, Lifeng Chen, Lujia Zhang, Xuedong Wang, an d Dongzhi Wei*, Protein Engineering of a Nitrilase from Burkholderia cenocepacia J2315 for Efficient and Enantioselective Production of (R)-o-Chloromandelic Acid, Applied Envi ronmental Microbiology, 2015 81:24 8469-8477.
2. Xin Gao, Chengcheng Zhao, Ting Yu, Shengli Yang, Yuhong Ren, Dongzhi Wei*, Constr uction of a reusable multi-enzyme supramolecular device via disulfide bond locking, Chem ical Communications, 2015, 51, 10131—10133.
3. Shujing Zhu , Xiaoqiang Ma , Erzheng Su, Dongzhi Wei*, Efficient hydration of 2-amino -2, 3-dimethylbutyronitrile to 2-amino-2, 3-dimethylbutyramide in a biphasic system via an easily prepared whole-cell biocatalyst, Green Chemistry, 2015, 17, 3992-3999.
4. Dongbing Cui, Lujia Zhang1, Shuiqin Jiang, Zhiqiang Yao, Bei Gao, Jinping Lin, Y. Ada m Yuan and Dongzhi Wei*, A computational strategy for altering an enzyme in its cofact or preference to NAD(H) and/or NADP(H), FEBS Journal, 2015,282(12):2339–2351.
5. Xin Gao, Shuai Yang, Chengcheng Zhao, Yuhong Ren*, Dong-Zhi Wei*,Artificial multi enzyme supramolecular device: highlyordered self-assembly of oligomeric enzymes in vitro and in vivo,Angewandte Chemie,2014,126(51):14251-14254.
6. Yao, Kang,Xu, Li-Qin,Wang, Feng-Qing*,Wei, Dong-Zhi*,Characterization and engi neering of 3-ketosteroid-Delta(1)-dehydrogenase and 3-ketosteroid-9 alpha-hydroxylase in Mycobacterium neoaurum ATCC 25795 to produce 9 alpha-hydroxy-4-androstene-3,17-dione through the catabolism of sterols,Metabolic Engineering,2014,24:181-191.
7 Zhang, Lujia,Tang, Xiaomang,Cui, Dongbing,Yao, Zhiqiang,Gao, Bei,Jiang, Shuiqi n,Yin, Bo,Yuan, Y. Adam,Wei, Dongzhi*, A method to rationally increase protein stability based on the charge-charge interaction, with application to lipase LipK107,Protei Science,2014,23(1):110-116.
8. Yin, Bo,Cui, Dongbing,Zhang, Lujia,Jiang, Shuiqin,Machida, Satoru,Yuan, Y. Ada m*,Wei, Dongzhi*,Structural insights into substrate and coenzyme preference by SDR f amily protein Gox2253 from Gluconobater oxydans,Proteins: Structure, Function, and Ge netics,2014,82(11):2925-2935.
9. Liu, Xu,Wang, Chao,Zhang, Lujia,Yao, Zhiqiang,Cui, Dongbing,Wu, Liang,Lin, J inping*,Yuan, Yu-Ren Adam,Wei, Dongzhi*,Structural and mutational studies on an a ldo-keto reductase AKR5C3 from Gluconobacter oxydans,Protein Science,2014,23(1 1):1540-1549.
10. Gao, Xin,Ni, Kefeng,Zhao, Chengcheng,Ren, Yuhong*,Wei, Dongzhi*,Enhancement of the activity of enzyme immobilized on polydopamine-coated iron oxide nanoparticles by rational orientation of formate dehydrogenase,Journal of Biotechnology,2014,188: 36-41.
11. You PY, Qiu J, Su EZ, Wei DZ*, Carica papaya Lipase Catalysed Resolution of β-Amin o Esters for the Highly Enantioselective Synthesis of (S)-Dapoxetine, European Journal of Organic Chemistry, 2013, 3: 557-565.
12. Ni, Kefeng; Lu, Huimin; Wang, Cunxun; Black, Kvar C. L.; Wei, Dongzhi; Ren, Yuhong, Messersmith, Phillip B., A novel technique for in situ aggregation of Gluconobacter oxyda ns using bio-adhesive magnetic nanoparticles, Biotechnology and Bioengineering, 2012, 10 9(12):2970-2977.
13. Ni K, Zhou X, Zhao L, Wang HL, Ren YH*, Wei DZ*, Magnetic Catechol-Chitosan wit h Bioinspired Adhesive Surface: Preparation and Immobilization of v-Transaminase, PLoS One, 2012, 7(7) :e41101.
14. Zhang C, Fan K, Zhang W, Zhu R, Zhang L, Wei DZ*. Structure-based characterization of canine-human chimeric uricases and its evolutionary implications. Biochimie. 2012,94 (6):1412-1420.
15. Yao K, Wang FQ, Zhang HC, Wei DZ*. Identification and engineering of cholesterol oxi dases involved in the initial step of sterols catabolism in Mycobacterium neoaurum. MET ABOLIC ENGINEERING, 2013, 15:75–87.
16. Liu X, Yuan Z, Yuan Y, Lin JP, Wei DZ*. Biochemical and structural analysis of Gox2 181, a new member of the SDR superfamily from Gluconobacter oxydans. Biochemical a nd Biophysical Research Communications. 2011, 415(2): 410-415.
17. Wang JQ, Tao XY, Zhang YF, Wei DZ*, Ren YH* et al. Reversion of multidrug resistance by tumor targeted delivery of antisense oligodeoxynucleotides in hydroxypropyl-chitosa n nanoparticles. Biomaterials, 2010, 31(15):4426-4433.