biography
2015 – Present Director Basic Science Graduate Programs Science Faculty Pontificia Universidad Javeriana. Bogotá – Colombia.
2001 – 2015 Academic Director Medical Microbiology Specialization Science Faculty Pontificia Universidad Javeriana. Bogotá – Colombia.
2001 – Present Director Microorganism Culture Collection (CMPUJ) Colombian National Register: 148 conferred by Alexander Von Humboldt Institute Associate Member of World Federation of Culture Collection (WFCC) WFCC Register: 857 Pontificia Universidad Javeriana. Bogotá – Colombia
Area of Interest
1) Helicobacter pylori and related gastroduodenal diseases.
2) Gastric cancer and the role of Helicobacter pylori infection in its development.
3) H. pylori eradication and resistant mechanisms to antimicrobials agents.
4) Gastrointestinal infections and their relationship with microbiome.
5) Human microbiome.
6) Diagnosis and pathogenesis of bacterial infectious diseases, molecular biology, molecular characterization of Helicobacter pylori, conservation and preservation of microorganisms.
7) Teaching and research in microbiology.
top publication
1) Trespalacios A.A, Rimbara E, Otero W, Redy R, and Graham DY. Improved Allele-Specific PCR assays for detection of clarithromycin and fluoroquinolone resistant of Helicobacter pylori in gastric biopsies: Identification of N87I mutation in GyrA. Diagnostic Microbiology & Infectious Disease. 2015 Apr;81(4):251-5. DOI: 10.1016/j.diagmicrobio.2014.12.003. http://www.ncbi.nlm.nih.gov/pubmed/25600075
2) Acosta CP, Hurtado FA, Trespalacios A.A. Determinación de mutaciones de un solo nucleótido en el gen 23S rRNA de Helicobacter pylori relacionadas con resistencia a claritromicina en una población del departamento del Cauca, Colombia. Biomédica. 2014. 34(Supl.1):156-62. file:///D:/Documentos%20Perfil/Descargas/1649-9070-1-PB%20(5).pdf
3) Trespalacios A.A, Otero W, Caminos JE, Mercado MM, Avila JM, Rosero LE, Arevalo A, Poutou-Piñales RA and Graham DY. Phenotypic and Genotypic Analysis of Clarithromycin-Resistant Helicobacter pylori from Bogotá D.C., Colombia. Journal of Microbiology. 2013 Vol. 51, No. 4, pp. 448–452. http://link.springer.com/article/10.1007%2Fs12275-013-2465-6
4) Ramírez-Bulla P, Mercado-Reyes M, Trespalacios-Rangel AA, Avila-Coy J; Otero-Regino W. Estado actual de la resistencia de Helicobacter pylori a tetraciclina: revisión sistemática de la literatura. Universitas Scientiarum. 2012, Vol. 17 N° 2: 216-229. http://www.scielo.org.co/pdf/unsc/v17n2/v17n2a08.pdf
5) Graham DY, Trespalacios AA. Treatment of Helicobacter pylori in Latin America. Lancet. 2012. Feb. 4: 379(9814): 408 http://www.ncbi.nlm.nih.gov/pubmed/?term=Lancet.+2012.+Feb.+4%3A+379(9814)%3A+408
6) Li Y, Rimbara E, Thirumurthi S, Trespalacios A, Reddy R, Sabounchi S, Attumi TA, Graham Dy. Detection of clarithromycin resistance in Helicobacter pylori following noncryogenic storage of rapid urease test for 30 days. Journal Digestive Disease. 2012. Jan; 13(1): 54-9. http://www.ncbi.nlm.nih.gov/pubmed/22188917
7) Duque-Jamaica R, Arévalo-Galvis A, Poutou-Piñales RA, Trespalacios AA. Sequential statistical improvement of the liquid cultivation of Helicobacter pylori. Helicobacter. 2010 Aug;15(4):303-12. http://onlinelibrary.wiley.com/doi/10.1111/j.1523-5378.2010.00763.x/pdf
8)Trespalacios A, Otero W, Mercado M. Resistencia de Helicobacter pylori a metronidazol, claritromicina y amoxicilina en pacientes colombianos. Revista Colombiana de Gastroenterología. Vol. 25 No 1 enero – marzo de de 2010. http://www.scielo.unal.edu.co/scielo.php?pid=S0120-99572010000100009&script=sci_arttext&tlng=es
9) Arévalo G. A, Trespalacios A.A, Otero W. Importancia de la proteína cagA en infección por Helicobacter pylori. Revista Colombiana de Gastroenterología. 2009; 24 (4): 388-395. http://www.scielo.org.co/pdf/rcg/v24n4/v24n4a09.pdf
10) Carreño Y, Mercado M, Trespalacios A, Otero W. Comparación de la prueba de antígenos fecales (ELISA) y test de aliento de la urea frente a histología para el diagnóstico de Helicobacter pylori: Revisión sistemática de la literatura. Revista Colombiana de Gastroenterología. Vol. 24 No 4. 2009. http://www.scielo.org.co/pdf/rcg/v24n4/v24n4a07.pdf
Books Chapters
1) Trespalacios A.A. Chapter 6: Mechanisms of infection. Pages: 56-73. In: Hospital Infections. Editorial Médica Panamericana. Third edition. 2010. ISBN: 9789588443041.
2) Otero W, Gomez M, Trespalacios A.A. Helicobacter pylori after all. Selected topics of Gastroenterology. First edition. Bogota, D.C.: Issue 60. Colombian Association of Gastroenterology, 2007.
3) Trespalacios A.A, Diaz G.D. Immune System. Chapter 5. Pages 37 - 46. Gastroenterology and Hepatology . Editorial Celsus. Second Edition. 2005 - Bogota, Colombia.
4) Trespalacios A.A, Diaz G.D. The intestine as a lymphoid organ. Chapter 6. Pages 47- 56. Gastroenterology and Hepatology. Editorial Celsus . Second Edition. 2005. Bogotá - Colombia.
Books
1) Trespalacios A.A. Cellular Biology. Bogota DC. First Edition. UNAD Editorial. 2002. 432 pages.
2) Trespalacios A.A. Biochemistry. Bogota First Edition. UNAD Editorial. 2002. 270 pages.
Paper Presentations in Conferences, Seminars and Invited Lectures
1) Arevalo A, Trespalacios AA, Otero W y Mercado M. CYP2C19 genotypes and future applications in personalized therapies for Helicobacter pylori eradication. XXVIIth International Workshop of the Helicobacter Study Group, Rome, Italy, September 11-13, 2014.
2) Trespalacios AA, Mercado MM, Otero W. Efficacy of first-line Helicobacter pylori eradication treatment with two triple regimens with levofloxacin. DDW2014. Digestive Disease Week. Mayo 2014. McCormick Place, Chicago, Illinois, USA. Journal of Gastroenterology.