biography
Dr. Jae-Hwan Nam is currently an associated professor of the Department of Biotechnology at the Catholic University of Korea. He received his MS and PhD from the Department of Biology at Korea University, and has worked as a senior research scientist at the KNIH in Seoul and as postdoctoral researcher at the NIAID, NIH, in Bethesda. As a virologist, he has researched about vaccine, viral vector systems, virus-induced signal pathways, and more recently about virus-induced obesity. He has published more than 81 scientific articles, including some on the epidemiology of Adenovirus 36 infection in Korea and the underlying inflammatory mechanisms.
Area of Interest
He is interesting about ‘infectobesity’, the role of inflammation in obesity, and the development of vaccine for infectious and chronic diseases.
top publication
1. Proof-of-concept for a virus-induced obesity vaccine; vaccination against the obesity agent adenovirus 36. Na HN, Nam JH. Int J Obes (Lond). 2014
2. Reduction of adenovirus 36-induced obesity and inflammation via the use of mulberry extract. Na HN, Park S, Jeon HJ, Kim HB, Nam JH. Microbiol Immunol. 2014
3. Obesity-induced Chronic Inflammation is Associated with the Reduced Efficacy of Influenza Vaccine. Hye-Lim Park, Seung-Hyun Shim, Eun-Young Lee, Wha-Jung Cho, Sooho Park, Hyun-Jung Jeon, Sun-Young Ahn, Hun Kim and Jae-Hwan Nam* Hum Vaccin Immunother 2014. 10(5).
4. Prophylactic and therapeutic vaccines for obesity. Na HN, Kim H, Nam JH. Clin Exp Vaccine Res. 2014 Jan;3(1):37-41.
5. Genomic stability of adipogenic human adenovirus 36. Jae-Hwan Nam*, Ha-Na Na, Richard L. Atkinson, Nikhil V. Dhurandhar*. International Journal of Obesity. 2014 3(1):37-41
6. Novel Role of Invariant Natural Killer T-cell in Glycemic Control: Regulation by human Adenovirus 36. Sooho Park and Jae-Hwan Nam*. Journal of Bacteriology and Virology 2013. 43(3):229-232
7. The yesterday, today, and tomorrow of pathogen-induced obesity. Ha-Na Na and Jae-Hwan Nam* The Korean Journal of Obesity 2013 22(4):187-196.
8. Histone deacetylase inhibitors suppress coxsackie virus B3 growth in vitro and myocarditis induced in mice. S.-H. SHIM, J.-H. PARK, M. B. YE, J.-H. NAM*. Acta Virologica. 2013. 57:462-466
9. Immunogenicity and safety of H1N1 influenza hemagglutinin protein expressed in a baculovirus system. Ha-Na Na, Kyung Hyun Kim, Man Ki Song, Hye-lim Park, Eun-young Lee, Seung-Hyun Shim, Sooho Park and Jae-Hwan Nam* 4 Microbiology and Immunology. 2013, 57(9):660-4
10. Harnessing the Beneficial Properties of Adipogenic Microbes for Improving Human Health. Dhurandhar NV, Geurts L, Atkinson RL, Casteilla L, Clement K, Gerard P, Vijay-Kumar M, Nam JH, Nieuwdorp M, Trovato G, Sørensen TIA, Vidal-Puig A, Cani PD. Obesity Reviews. 2013
11. Why is not there a match between the serological and genomic prevalence of adenovirus 36? Nam JH. J Clin Virol. 2013, 56:370-371 (*Corresponding author) 12. IK induced by Coxsackievirus B3 infection transiently down-regulates expression of MHC class II through increasing cAMP. Hye-Lim Park, Yeon-Jung Kim, Ha-Na Na, Mi-Young Park, Joo-Young Kim, Cheol-Won Yun, Jae-Hwan Nam* Viral Immunology. 2013 26;1:13-24
13. Black soybean anthocyanins inhibit adipocyte differentiation in 3T3-L1 cells. Kim HK, Kim JN, Han SN, Nam JH, Na HN, Ha TJ. Nutr Res. 2012, Oct;32(10):770-7.
14. A peptide vaccine based on a B-cell epitope on the VP1 protein of enterovirus 70 induces a strong antibody response. Park KB, Lim BK, Ye MB, Chung SY, Nam JH. Acta Virol. 2012;56(4):337-42.
15. Development of an in vitro antigen-detection test as an alternative method to the in vivo plaque reduction neutralization test for the quality control of Japanese encephalitis virus vaccine. DoKeun Kim, Hye-Youn Kim, Joo-Young Kim, Michael B. Ye, Kee-Bum Park, Euiri Han, Jae Ok Kim, Sang Ja Ban, Seung-Hwa Hong, Yong Keun Park, and Jae-Hwan Nam* Microbiology and Immunology 2012, 56(7):463-471
16. Coxsackievirus B3 used as a gene therapy vector to express functional FGF2 D-S Kim1,4, H Kim2,4, S-H Ssim1,4, C Kim2, M Song2, Y-H Kim2, Y-W Jung3, and J-H Nam1 2012 Gene Therapy. 2012 Apr;44(2):176-82
17. Adenovirus 36 as an Obesity Agent Maintains the Obesity State by Increasing MCP-1 and Inducing Inflammation. Ha-Na Na and Jae-Hwan Nam* Journal of Infectious Diseases. 2012, 205:914-922
18. A mechanism of immunoreceptor tyrosine-based activation motif (ITAM)-like sequences in the capsid protein VP2 in viral growth and pathogenesis of Coxsackievirus B3. Dae-Sun Kim, Jung-Hyun Park, Joo-Young Kim, DoKeun Kim, Jae-Hwan Nam* Virus Genes. 2012, 44:176-182
19. Regulation of innate immunity via MHC class II-mediated signaling; Non-classical role of MHC class II in innate immunity (Letter to the Editor). Hye-Lim Park and Jae-Hwan Nam* Journal of Bacteriology and Virology. 2011, 41:3:1-3.
20. Infectobesity: a new area for microbiological and virological research. Ha-Na Na and Jae-Hwan Nam* Journal of Bacteriology and Virology. 2011, 41:2:65-76.
21. Development of a Gene Therapy Method for Cervical Cancer Using Attenuated Coxsackievirus B3 as a Vector System. Seung-Hyun Shim, Yeon-Jung Kim, Dae-Sun Kim, Jae-Hwan Nam* Journal of Bacteriology and Virology. 2011, 41:2:123-130.
22. RNA interference to granulin–epithelin precursor prevents hepatocellular carcinoma growth: its application as a therapeutic agent. MI-YOUNG PARK1†, YOON SHIN PARK, JAE-HWAN NAM* International J Oncology. 2011, 39:853-861.
23. Novel genes and cellular pathways related to infection with adenovirus-36 as an obesity agent in human mesenchymal stem cells. Ha-Na Na, Hyongbum Kim, and Jae-Hwan Nam* International J Obesity. 2012 36:195-200
24. Association of human adenovirus-36 in overweight Korean adults. Ha-Na Na, Jihye Kim, Hong Soo Lee, Kyung Won Shim, Heejin Kimm, Sun Ha Jee, Inho Jo, Jae-Hwan Nam*. International J Obesity. 2011 36:281-285.
25. Chk1 and Hsp90 cooperatively regulate phosphorylation of endothelial nitric oxide sysnthease at serine 1179. J-H Park, W-S Kim, J Y Kim, M-H Park, Jae-Hwan Nam, C-W Yun, Y-G Kwon, I Jo. Free Radical Biology & Medicine 2011 51(12):2217-2226