biography
Dr. Wei Xu background is primarily on molecular biology and genomics. His PhD research (Dr. Mohamed Faisals Laboratory) focused on understanding the molecular mechanism of underwater adhesion employed by zebra mussel (Dreissenapolymorpha) in the Great Lakes area. His postdoc training (Dr. Thomas Mustoes Laboratory) was on mechanistic study of skin wound repair and tissue regeneration in human medicine. Dr. Xu started his research in LSU Agriculture Center as an Assistant Professor in 2015. He continuously applied molecular biology and genomic methods on a wide range of species in Aquaculture.
Area of Interest
1)genetic pathway analyses in the Eastern oyster (Crassostreavirginica) in the adaption of environmental stresses
2)molecular mechanism of larva development of C. virginica
3)mechanism of American alligator (Alligator mississippiensis) in skin development and wound repair
4)host response of (Procambarusclarkii) in response to the infection of White Spot Syndrome Virus (WSSV)
5) alteration of gene expression during fish gametes cryopreservation.
top publication
1. Wei Xu, Seok Jong Hong, Michael Zeitchek, Garry Cooper, ShengxianJia, Ping Xie, Hannan A. Qureshia, AimeiZhong, Marshall D. Porterfield, Robert D. Galiano, D. James Surmeier, Thomas A. Mustoe: Transepidermal Water Loss Induces Sodium Flux and Regulates Inflammatory Pathways through Epithelial Sodium Channel (ENaC) in Skin, 2014 J. Invest.Dermatol. Nov 5. doi: 10.1038/jid.2014.477.PMID:25371970.
2. Wei Xu, ShengxianJia, Ping Xie, AimeiZhong, Robert D. Galiano, Thomas A. Mustoe, Seok Jong Hong: The Expression of Proinflammatory Genes in Epidermal Keratinocytes Is Regulated by Hydration Status. 2013, J Invest Dermatol. doi: 10.1038/jid.2013.425. PMID: 24226202.
3. Seok Jong Hong, Eugene Park, Wei Xu, ShengxianJia, Robert D. Galiano, and Thomas A. Mustoe: Response of human mature adipocytes to hypoxia-reoxygenation. 2014, Cytotherapy, 16(12):1656-65.PMID:25231891.
4. Kai P. Leung; Peter D\'Arpa; Akhil K. Seth; Matthew R. Geringer; Marti Jett; Wei Xu; Seok J. Hong; Robert D. Galiano; Tsute Chen; Thomas A. Mustoe: Dermal wound transcriptomic responses to Infection with Pseudomonas aeruginosa versus Klebsiellapneumoniaeina rabbit ear wound model. 2014, BMC ClinPathol. 14:20. PMID: 25035691.
5. Claudia Chavez-Munoz, Khang Nguyen, Wei Xu, Seok-Jong Hong, Thomas A. Mustoe, Robert D. Galiano: Transdifferentiation of Adipose-derived Stem Cells into Keratinocyte-like cells: Engineering a Stratified Epidermis. 2013, Plos One, 8(12):e80587. PMID: 24312483.
6. Seok Jong Hong, Sheng-Xian Jia, Ping Xie, Wei Xu, Kai Leung, Thomas Mustoe, RobertGaliano: Topically Delivered Adipose Derived Stem Cells Show an Activated-Fibroblast Phenotype and Enhance Granulation Tissue Formation in Skin Wounds. 2013, Plos One, 8(1): e55640. PMID: 23383253.
7. Wei Xu, Seok Jong Hong, ShengxianJia, Yanan Zhao, Robert Galiano, and Thomas Mustoe: Application of a partial thickness human ex vivo skin culture model in cutaneous wound healing study. 2012, Lab Invest, 92:584-599. PMID:219478584
8. Thomas Loch, Rakesh Kumar, Wei Xu, and Mohamed Faisal: CarnobacteriumMaltaromaticus infections in Feral Oncorhynchus spp. (Family Salmonidae) in Michigan. 2011, J Microbiol. 49 (5): 703-713. PMID: 22068485
9. Wei Xu and Mohamed Faisal: Factorial microarray analysis of zebra mussel (Dreissenapolymorpha: Dreissenidae, Bivalvia) adhesion. 2010. BMC Genomics. 11: 341-357. PMID: 20509938.
10. Wei Xu and Mohamed Faisal: Gene expression profiling during the byssogenesis of zebra mussel (Dreissenapolymorpha). 2010. Mol Genet Genomics. 283 (4): 327-339. PMID: 20148265
11. Wei Xu and Mohamed Faisal: Defensin of the zebra mussel (Dreissenapolymorpha): molecular structure, in vitro expression, antimicrobial activity, and potential functions. 2010. MolImmunol. 47(11-12):2138-2147. PMID: 20537393
12. Wei Xu and Mohamed Faisal: Development of a cDNA microarray of zebra mussel (Dreissenapolymorpha) foot and its use in understanding underwater adhesion. 2009. Gene 436 (1-2): 71-80. PMID: 19393183
13. Wang L, Song L, Zhao J, Qiu L, Zhang H, Xu W, Li H, Li C, Wu L, Guo X: Expressed sequence tags from the zhikong scallop (Chlamysfarreri): discovery and annotation of host-defense genes. Fish Shellfish Immunol. 2009. 26(5) :744-750. PMID: 19328855
14. Wei Xu and Mohamed Faisal: Identification of the molecules involved in zebra mussel (Dreissenapolymorpha) hemocytes host defense. 2009. Comp BiochemPhysiol B. 154 (1): 143-149. PMID: 19482094
15. Zhu L, Song L, Xu W, Qian PY: Identification of a C-type lectin from the bay scallop Argopectenirradians. MolBiol Rep. 2009. 36(5):1167-1173. PMID: 18622759
16. Wei Xu and Mohamed Faisal: Putative identification of expressed genes associated with attachment of zebra mussel (Dreissenapolymorpha). 2008. Biofouling 24: 157-161
. 17. Thomas P. Loch, Wei Xu, Scott M. Fitzgerald, Mohamed Faisal: Isolation of a Carnobacteriummaltaromaticum-like bacterium from systemically infected Lake Whitefish (Coregonusclupeaformis). 2008. FEMS Microb Lett. 288 (1): 76-84. PMID: 18793198
18. Zhu L, Song L, Mao Y, Zhao J, Li C, Xu W. A novel serine protease with clip domain from scallop Chlamysfarreri. MolBiol Rep. 2008. 35(2): 257-264. PMID: 17484057
19. Zhu L, Song L, Zhang H, Zhao J, Li C, Xu W. Molecular cloning and responsive expression to injury stimulus of a defender against cell death 1 (DAD1) gene from bay scallops Argopectenirradians. 2008. MolBiol Rep. 35(2): 125-132. PMID: 17294251
20. Zhu L, Song L, Xu W, Qian PY: Molecular cloning and immune responsive expression of a novel C-type lectin gene from bay scallop Argopectenirradians. Fish Shellfish Immunol. 2008. 25(3):231-238. PMID: 18640058