Sandra S. Hatch

Professor, Vice Chair

Texas, USA


Dr. Sandra Hatch (Sunny) is a tenured professor and Vice Chairman of Radiation Oncology at the University of Texas Medical Center in Galveston, Texas. Her practice is focused on gynecologic and breast malignancies. She is an established educator and serves as the Department’s  Residency Program Director. In addition she is the Clinic Director for the five practice locations for the department’s operations. She holds two endowments. She is the Irma Labardini Mendoza and Jesse Jesus Mendoza Distinguished Chair in Breast and Gynecologic Malignancies established for her by a grateful patient. She also holds the Ruth Levy Kempner Professorship in Breast Cancer established in response to her leadership in breast cancer patient centered care. Dr. Hatch received her medical training at the University of Texas at the Health Science Center at Houston, Texas, followed by a Transitional Internship at the Central Texas Medical Foundation in Austin, Texas. Residency in Radiation Oncology was achieved at Baylor College of Medicine, Houston, Texas


Area of Interest

The role of inflammation, hypermethylation, and mutation in endometrial cancer development The UNC-45 Molecular Chaperone as a Biomarker and Therapeutic Target In Breast Cancer 2-Methoxyestradiol, an endogenous estrogen metabolite, and its role as radiosensitizer in the radioresistant breast cancer cell line MCF-7/FIR thorough multiple mechanisms Molecular Profile of LCIS, Lobular Cancer and Pleomorphic Cancer Cancer Cachexia in Cervical Cancer Patients; Nutrition and Anabolic Interventions in Cancer Cachexia Gynecologic Malignancy and Treatment Outcomes in the Senior Oncology Patient.

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1. Santoso, J.T., Lucci III, J.A., Coleman, R.L., Hatch, S.S., Wong, P., Miller D.S., Mathis, J.M.:Does glutamine supplementation increase radioresistance in squamous cell carcinoma of the cervix?. Gynecologic Oncology 71(3):359-363, December 1998. DOI:10.1006/gyno.1998.5175. PMID 9887231.
2. Culp L., Crowder S., Hatch, S.: A rare association of Sweet’s Syndrome with cervical cancer. Gynecologic Oncology 95(2) 396-399, Nov 2004. DOI:10.1016/j.ygyno.2004.06.050. PMID 15491764.
3.Bing, Z., Levine, Lyuba, Lucci, J.A., Hatch, S.S., Eltorky, M.A.: Primary Small Cell Neuroendocrine Carcinoma of the Vagina A Clinicopathologic Study. Archives of Pathology & Medicine Vol 128 (8), 857-862, August 2004. PMID 15270619
4. Morgan, P.F., Chandru, S.,Hatch, S.S., Hawkins, H.K., Abegboyega, PA, Eltorky, M.A.: Low-Grade Myofibroblastic Sarcoma of the Breast. Journal of Clinical Oncology, Vol 23, Issue 25:6249-6251, Sep 1, 2005. DOI 10.1200/JCO.2005.06.213. PMID 16135491.
5. Cavey, Matthew, Bayouth J. E., Endres, E.J., Pena J.M., Hatch, S. : Dosimetric comparison of conventional and forward-planned intensity modulated techniques for comprehensive locoregional irradiation of post-mastectomy left breast cancers. Medical Dosimetry Vol 30 (2),107-116,2005. PMID 15922178. DOI:10.1016/j.meddos.2005.02.002.
6. Caban, M.E., Freeman, J.L., Zhang, D.D., Jansen, C., Ostir, G., Hatch, S.S., Goodwin, J.S.: The relationship between depressive symptoms and loss of shoulder mobility among older women: assessment at one year after breast cancer diagnosis. Journal of Clinical Rehabilitation 2006 Jun; 20(6): 513-522. PMID 16892933.
7. Gunn, Brandon G., Anderson, Karl E., Patel, Abhilasha J., Gallegos, Juan Hallberg, Csilla, Sood, Gagan, Hatch, Sandra S., Sanguineti, Giuseppe: Severe radiation therapy-related soft tissue toxicity in a patient with porphyria cutanea tarda: a case report and literature review. Head and Neck 2010 Aug; 32(8):1112-7. DOI 10.1002/hed.21161. PMID 19536857.
8. Samper-Ternent, Rafael; Zhang, Dong; Kuo, Yong-Fang; Hatch, Sandra; Freeman, Jean: Late GI and Bladder Toxicities after Radiation for Uterine Cancer. Gynecologic Oncology 2011 Feb; Vol 120 (2) 198-204. DOI:10.1016/j.ygyno.2010.10.017. PMID 21084108.
9. Salama, Salama; Diaz-Arrastia, Concepcion; Patel, Deepa; Botting, Shaleen; Hatch, Sandra: 2-Methoxyestradiol, an endogenous estrogen metabolite, radiosensitizes the radioresistant breast cancer cell line MCF-7/FIR thorough multiple mechanisms International Journal of Radiation Oncology, Biology, Physics Vol 80, Number 1, May 1, 2011, 231-239. DOI: 10.1016/j.ijrobp.2010.10.080. PMID 21392897.
10. Dillon EL, Basra G, Horstman AM, Casperson SL, Randolph KM, Durham WJ, Urban RJ, Diaz-Arrastia C, Levine L, Hatch SS, Willis M, Richardson G, Sheffield-Moore M. Cancer Cachexia and Anabolic Interventions: A Case Report. J Cachexia Sarcopenia Muscle. May 2012; DOI 10.1007/s13539-012-0066-6. PMID 22385408.
11. Samper-Ternent, Rafael A; Humera, Asem; Zhang, Dong D; Kuo, Yong-Fang; Hatch, Sandra S.; Freeman, Jean; Berenson, Abbey B.: The effect of postoperative beam, implant, and combination radiation therapy on GI and bladder toxicities in women with Stage I uterine cancer. Journal of Geriatric Oncology.3(2012), pp344-350 [Published online 9/15/2012].DOI 10.1016/j.jgo.2012.06.005 PMID 23138191
12. Howland, Nicholas K., Driver, Teryn D., Sedrak, Michael P, Wen, Xianfeng Wen, Dong, Wenli, Hatch, Sandra, Eltorky, Mahmoud A., Chao,Celia: Lymph Node Involvement In Immunohistochemistry-Based Molecular Classifications of Breast Cancer. Journal of Surgical Research. July, 2013. DOI 10.1016/j.jss.2013.06.048
13. Patel, A.J., Gajjar, S., Abel, J., Hatch, S: The Treatment of Scleroderma with Repeat Radiation: a Case Report and Literature Review. Applied Radiation Oncology. September 2013; pages 27-28.
14. Cox, John A., Sevak, P. R., Grumbles, L. L., Swanson, T. A., Hatch, S. S.: Hypofractionated Radiotherapy for Palliation of Myelofibrosis Related Lower Extremity Pain Syndrome. Journal of Pain and Symptom Management 2013.


1. Hatch,S.S.: Principles of Radiation Oncology; GYN-ONCOLOGY Handbook, Santoso, JT, Lucci, JA, Coleman, R. McGraw-Hill, 2001.
2. Caban, M.E. and Hatch, S.: Lymphedema; In Frontera WR, Silver JK, Robinson LR (ed): Clinical Physical Medicine: Musculoskeletal Disorders, Pain and Rehabilitation, 2nd Edition, Philadelphia, Elsevier. (2007)


1. Hatch, S.S., Dennis, W.S., Jhingran, A.J.: Intraoperative placement of radioactive gold grain for non-small cell lung carcinoma with poor prognostic features. Radium Society Meeting, Montreal, Canada, May 1991.
2. Garlitos, D. R., Hatch, S. S., Morrill, S., Ellison, B.: Neoadjuvant Cyclophosamide and 5-Fluorouracil and Concurrent Radiation Therapy in Locally Advanced Breast Cancer, Review of 15 year Institutional Experience at UTMB. Los Angeles Radiological Society, 51st Annual Midwinter Radiation Oncology Conference, January 22 – 24, 1999, Los Angeles, California.
3. Villanueva-Meyer, J., Briscoe, E., Fleming, D., Cesani, F., Hatch, S.S., Balbastro, E., Velasquez, W.: Scintimammography to follow the response to treatment in advanced Breast cancer. 46th Annual Meeting of the Society of Nuclear Medicine 1999. Meeting Abstract 553. Journal of Nuclear Medicine Vol 40 (5), 137, Supplement S, May 1999.
4. Filipowicz, E.A., Garlitos, D., Hatch,S., Gatalica, Z.: Pathologic Predictors of Response to Neoadjuvant Therapy for Mammary Carcinoma. Session Breast Cancer II: Prognostic Biomarkers. American Association for Cancer Research (AACR), April 3, 2000, San Francisco, California.
5. Colman, M., Bayouth J., Hatch, S., Yang, T., Chan, R., Morrill, S.: Intensity Modulated Radiation Therapy (IMRT) – A Pragmatic Solution To An Infinitely Complex Problem. Texas Radiologic Society (TRS), April 2000.
6. Lee, C.M., Crowder, S.E., Grady, J.J., Hatch, S., Lucci, J.A. : Evaluation of Recurrence Rates In Stage IB1 Squamous Cell Carcinoma Of The Cervix Treated With Surgery Compared to Radiation Therapy. Western Association of Gynecologic Oncologists (WAGO), May 2000.
7. Carroll, M.P., Velasquez, W., Li, Z., Indrikovs, A., Hatch, S., Soefje, S.A., Fung, F.K.: Phase I Trial of Sequential High-Dose Carboplatin, Topotecan and Etoposide with Autologous Stem Cell Transplantation for Refractory Malignancies. ASH, San Francisco, 2000. Meeting Abstract 1836. Blood, Volume 96 (Issue 11), 427A-427A, Part 1, Nov 16, 2000.
8. Smith, A., Bayouth J., Zhou, S., Pena, J., Endres, E.J., Hatch,S.S.: Dose Calculation Difference for Intracavitary Brachytherapy Using Conventional ICRU Guidelines and 3D Treatment Planning Systems. American Brachytherapy Society (ABS), May 19-22, 2001, Vancouver, British Columbia, Canada. Travel Award.
9. Smith, A.B., Bayouth, J.E., Zhou, S., Pena, J., Endres, E.J., Hatch, S.: Dose Calculation Difference for Intracavitary Brachytherapy Using Conventional ICRU Guidelines and Three-Dimensional Treatment Planning Systems. Proceedings of the 22nd Annual American Brachytherapy Society, 67, 2001.
10. Smith, A. B., DeLeon-McQuatters, T., Bayouth J. E., Pena, J., Endres, E. J., Hatch, S.: Three Dimensional Planning Significantly Improves Dose Homogeneity of Pelvic Sidewall Boost Plans Following Intracavitary Brachytherapy For Management of Cervical Carcinoma. American Radium Society (ARS), April 27 – May 1, 2002, Las Croabas, Puerto Rico. Meeting Abstract P11. Cancer Journal, Vol 8 (6), 498, Nov-Dec 2002. DOI:10.1097/00130404-200211000-00056.
11. Culp, L., Bayouth J., Colman M., Pena J., Hatch S. : Radiation Dose Reduction To The Optic Pathway In A Pediatric Patient With Gliosarcoma: A Comparison Of 3-D Conformal Radiation Therapy To Intensity Modulated Radiation Therapy. 10th International Symposium on Pediatric Neuro-Oncology (ISPNO), June 9-12, 2002, London, England. Neuro-Oncology 5(1): page 34, 2003.