Sha Xiao Chang

Associate Professor


Development, commissioning, and clinical implementation of an inhouse linac-based radiosurgery treatment system (hardware and software). The radiosurgery system was routinely used until it was replaced by Cyberknife in 2006.Commissioning and clinical implementation of Nucletron HDR service.Development of a dose optimization algorithm for compensator- IMRT and implementation of it in in-house treatment planning system PLUNC


Area of Interest

Radiation Oncology

top publication

Refereed Articles/book chapters
1. Pavel Chtcheprov, Laurel Burk, Hong Yuan, Christina Inscoe, Rachel Ger, Michael Hadsell, Jianping Lu, Sha Chang, Otto Zhou, Physiologically gated microbeam radiation using a field emission x-ray source array, Med Phys (accepted)
2. Mike Hadsell, Guohua Cao, Jian Zhang, Laurel Burk, Torsten Schreiber, Eric Schreiber, Sha Chang, Jianping Lu, Otto Zhou, Pilot study for compact microbeam radiation therapy using a carbon nanotube field emission micro-CT scanner, Med Phys (accepted)
3. Andrew N Fontanella1,a, Mary-Keara Boss2, Michael Hadsell3,b, Jian Zhang3,4,c, Thies Schroeder5, Katherine G Berman6, Gregory M Palmer5, Sha Chang3,4, Mark W Dewhirst1,5,* Effects of High-Dose Microbeam Irradiation on Tumor Microvascular Function and Angiogenesis, Radiation Research (submitted)
4. Lei Zhang, Hong Yuan, Laurel M Burk, Christy R Inscoe, Michael J Hadsell, Pavel Chtcheprov, Yueh Z Lee, Jianping Lu, Sha Chang and Otto Zhou, Image-guided microbeam irradiation to brain tumour bearing mice using a carbon nanotube x-ray source array Phys. Med. Biol. 59 (2014) 1–21
5. Jun Lian, Lulin Yuan, Yaorong Ge, Bhishamjit S Chera, David P Yoo, Sha Chang, Fangfang Yin, Q Jackie Wu Modeling the dosimetry of organ-at-risk in head and neck IMRT planning: an intertechnique and interinstitutional study, Medical physics 2013 40(12):121704 (Editor’s pick by Medical Physics journal)
6. Mike Hadsell Jerry Zhang Philip Laganis Frank Sprenger Jing Shan Lei Zhang Laurel Burk Hong Yuan Sha Chang JP Lu Otto Zhou A First Generation Compact Microbeam Radiation Therapy System Based on Carbon Nanotube X-ray Technology, APPLIED PHYSICS LETTERS 103, 000000 (2013)
7. Zijie Xu, Ronald Chen, Andrew Wang, Andrea Kress, Mark Foskey, An Qin, Timothy Cullip, Gregg Tracton, Sha Chang, Joel Tepper, Di Yan and Edward L Chaney Comparison of User-Directed and Fully Automatic Methods for Mapping a Radiation Beam Isocenter from Planning to Treatment Space in Image-Guided Radiotherapy for Prostate Cancer, International Journal of Medical Imaging 2013 (in Press)
8. Timothy Gershon, Andrew Crowther, Vivian Gama, Ariana Bevilacqua, Sha Chang, Hong Yuan, and Mohanish Deshmukh, Tonic activation of Bax primes neural progenitors for rapid apoptosis through a mechanism preserved in medulloblastoma, Neuroscience JN-RM-2602-13R1 33(46):18098-108.
9. Chen-Rui Chou, Brandon Frederick, Gig Mageras, Sha Chang, and Stephen Pizer. 2d/3d image registration using regression learning. Computer Vision and Image Understanding (CVIU), 2013. 117(9):1095-1106.
10. Pavel Chtcheprov, Michael Hadsell, Laurel Burk, Rachel Ger, Lei Zhang, Hong Yuan, Yueh Z. Lee, Sha Chang, Jianping Lu, Otto Zhou Physiologically gated microbeam radiation therapy using electronically controlled field emission x-ray source array Proc SPIE 03/2013; DOI:10.1117/12.2007998
11. Monte Carlo simulation of a compact microbeam radiotherapy system based on carbon nanotube field emission technology. EC Schreiber, SX Chang, Medical Physics 39 (8), 46692012 (featured in Physics Today September 2012)
12. Quantitative Assessment of Workload and Stressors in Clinical Radiation Oncology LM Mazur, MR Prithima, M Jackson, SX Chang, KD Burkhardt, RD Adams, EL Jones . International Journal of Radiation Oncology* Biology* Physics2012
13. Improving quality of patient care by improving daily practice in radiation oncology BS Chera, M Jackson, LM Mazur, R Adams, S Chang, K Deschesne, T Cullip, LB Marks Seminars in Radiation Oncology 22 (1), 77-8522012
14. Commentary: Adapting communication standards to enhance safety, LB Marks, SX Chang Practical Radiation Oncology 1 (4), 232-2342011
15. Empirical Evaluation of Workload of the Radiation Oncology Physicist During Radiation Treatment Planning and Delivery PR Mosaly, LM Mazur, M Jackson, SX Chang, KD Burkhardt, EL Jones, J Xu, J ... Proceedings of the Human Factors and Ergonomics Society Annual Meeting 55 (1 ...2011
16. A carbon nanotube field emission multipixel x-ray array source for microradiotherapy application S Wang, X Calderon, R Peng, EC Schreiber, O Zhou, S Chang Applied physics letters 98 (21), 213701-213701-382011
17. The challenge of maximizing safety in radiation oncology, LB Marks, M Jackson, L Xie, SX Chang, KD Burkhardt, L Mazur, EL Jones, P ...Practical Radiation Oncology 1 (1), 2-1482011
18. CR Chou, B Frederick, X Liu, G Mageras, S Chang, S Pizer Claret: A fast deformable registration method applied to lung radiation therapy, Fourth International (MICCAI) Workshop on Pulmonary Image Analysis, 113-124
19. Chen-Rui Chou, Brandon Frederick, Gig Mageras, Sha Chang, Stephen Pizer. Robust and Fast 2D/3D Image Registration using Regression Learning. Computer Vision and Image Understanding, Special issue: Shape Modeling in Medical Image Analysis (in press)
20. S. Wang, X. Calderon, R. Peng, E C. Schreiber, O Zhou, and S Chang, A carbon nanotube field emission multipixel x-ray array source for microradiotherapy application, Appl. Phys. Lett. 98, 213701 (2011); doi:10.1063/1.3595268