Mary Xiuyun Liu

Postdoctoral Researcher


Dr. Xiuyun Liu is a postdoctoral researcher in the Department of physiology nursing, University of California, San Francisco (UCSF), USA. She undertook her PhD in the Department of Clinical Neurosciences, University of Cambridge, UK. Dr. Liu has experience in clinical data analysis, especially cerebral autoregulation assessment, transcrannial doppler studies. Her research is related with treatment of traumatic brain injury patient.


Area of Interest

Dr. Liu is interested in biomedical data analysis. She also is keen on cerebral blood flow research. She has investigated different methods for cerebral autoregulation assessment, including time domain, frequency domain and time-frequency domain methods. She cares about biomedical engineering related projects.

top publication

1. Liu X, Czosnyka M, Donnelly J, Budohoski KP, Varsos GV, Nasr N, Brady KM, Reinhard M, Hutchinson PJ, Smielewski P. Comparison of frequency and time domain methods of assessment of cerebral autoregulation in traumatic. J. Cereb. Blood Flow Metab. 2014, 11:1-9. 2. Liu X, Czosnyka M, Pickard JD, Varsos GV, Nasr N, Smielewski P. Derangement of cerebral blood flow autoregulation during intracranial pressure plateau waves as detected by time and frequency-based methods. Acta Neurochir Suppl. 2016; 122:233-8. 3. Li Xiong*; Xiuyun Liu*; Ty Shang; Peter Smielewski; Joseph Donnelly; Zhen-ni Guo; Yi Yang; Thomas Leung; Marek Czosnyka; Rong Zhang; Jia Liu; Ka Sing Wong. Clinical applications of measuring impaired cerebral autoregulation in stroke. Journal of Neurology, Neurosurgery & Psychiatry (2017) 4. Xiuyun Liu, MSc, Marek Czosnyka, Joseph Donnelly, Marcel J. H. Aries, Ken Brady, Danilo Cardim, Chiara Robba, Manuel Cabeleira, Dong-Joo Kim, Christina Haubrich, Peter Smielewski. Cerebrovascular Pressure Reactivity Monitoring Using Wavelet Analysis in Traumatic Brain Injury Patients – accepted by PLOS Medicine (June, 2017) 5. Xiuyun Liu, Natasha M. Maurits, Marcel J.H. Aries, Marek Czosnyka, Joseph Donnelly, Danilo Cardim, Dong-Joo Kim, Celeste Dias, Manuel Cabeleira, Peter Smielewski. Monitoring of optimal cerebral perfusion pressure in traumatic brain injured patients using a multi-window weighting algorithm. J Neurotrauma. 2017 May 9. 6. Varsos GV, Budohoski KP, Czosnyka M, Kolias AG, Nasr N, Donnelly J, Liu X, Kim DJ, Hutchinson PJ, Kirkpatrick PJ, Varsos VG, Smielewski P. Cerebral Vasospasm affects Arterial Critical Closing Pressure. J Cereb Blood Flow Metab. 2015; 35(2):285-91. 7. Donnelly J, Czosnyka M, Harland S, Varsos GV, Cardim D, Robba C, Liu X, Ainslie PN, Smielewski P. Cerebral haemodynamics during experimental intracranial hypertension. J Cereb Blood Flow Metab. 2016;18. 8. Young AM, Donnelly J, Czosnyka M, Jalloh I, Liu X, Aries MJ, Fernandes HM, Garnett MR, Smielewski P, Hutchinson PJ, Agrawal S. Continuous Multimodality Monitoring in Children after Traumatic Brain Injury-Preliminary Experience. PLoS One. 2016 Mar 15;11(3). 9. Zhang Y, Liu X, Steiner L, Smielewski P, Feen E, Pickard JD, Czosnyka M. Correlation between cerebral autoregulation and carbon dioxide reactivity in patients with traumatic brain injury. Acta Neurochir Suppl. 2016;122:205-9. 10. Varsos GV, Czosnyka M, Smielewski P, Garnett MR, Liu X, Adams H, Pickard JD, Czosnyka Z. Cerebral critical closing pressure during infusion tests. Acta Neurochir Suppl. 2016;122:215-20. 11. Cardim D, Robba C, Bohdanowicz M, Donnelly J, Cabella B, Liu X, Cabeleira M, Smielewski P, Schmidt B, Czosnyka M. Non-invasive Monitoring of Intracranial Pressure Using Transcranial Doppler Ultrasonography: Is It Possible? Neurocrit Care. 2016 Mar 3. 12. Sykora M, Czosnyka M, Liu X, Donnelly J, Nasr N, Diedler J, Okoroafor F, Hutchinson P, Menon D, Smielewski P. Autonomic Impairment in Severe Traumatic Brain Injury. Crit Care Med. 2016 Jun;44(6):1173-81. 13. Cardim D, Czosnyka M, Donnelly J, Robba C, Cabella BC, Liu X, Cabeleira MT, Smielewsky P, Haubrich C, Garnett MR, Pickard JD, Czosnyka Z. Assessment of non-invasive ICP during CSF infusion test: an approach with Transcranial Doppler. Acta Neurochir (Wien). 2016 Feb;158(2):279-87. 14. Weersink CS, Aries MJ, Dias C, Liu MX, Kolias AG, Donnelly J, Czosnyka M, van Dijk JM, Regtien J, Menon DK, Hutchinson PJ, Smielewski P. Clinical and Physiological Events That Contribute to the Success Rate of Finding “Optimal” Cerebral Perfusion Pressure in Severe Brain Trauma Patients. Crit Care Med. 2015 Sep;43(9):1952-63. 15. Varsos GV, Czosnyka M, Smielewski P, Garnett MR, Liu X, Kim DJ, Donnelly J, Adams H, Pickard JD, Czosnyka Z. Cerebral critical closing pressure in hydrocephalus patients undertaking infusion tests. Neurol Res. 2015 Aug;37(8):674-82. 16. Sekhon MS, Griesdale DE, Czosnyka M, Donnelly J, Liu X, Aries MJ, Robba C, Lavinio A, Menon DK, Smielewski P, Gupta AK. The Effect of Red Blood Cell Transfusion on Cerebral Autoregulation in Patients with Severe Traumatic Brain Injury. Neurocrit Care. 2015 Oct;23(2):210-6. 17. J Simpson, N Sudhan, H Hare, J Donnelly, X Liu, F Aigbirhio, T Fryer, G Stocks-Gee, P Smielewski, D Bulte, and J Coles. Comparison of 15oxygen positron emission tomography and near-infrared spectroscopy for measurement of cerebral physiology. Crit Care. 2015; 19(Suppl 1): P445. 18. Meel-van den Abeelen AS, Simpson DM, Wang LJ, Slump CH, Zhang R, Tarumi T, Rickards CA, Payne S, Mitsis GD, Kostoglou K, Marmarelis V, Shin D, Tzeng YC, Ainslie PN, Gommer E, Müller M, Dorado AC, Smielewski P, Yelicich B16, Puppo C, Liu X, Czosnyka M, Wang CY, Novak V, Panerai RB, Claassen JA. Between-centre variability in transfer function analysis, a widely used method for linear quantification of the dynamic pressure-flow relation: the CARNet study. Med Eng Phys. 2014 May;36(5):620-7. 19. Nasr N, Czosnyka M, Pavy-Le Traon A, Custaud MA, Liu X, Varsos GV, Larrue V. Baroreflex and Cerebral Autoregulation Are Inversely Correlated. Circ J. 2014;78(10):2460-7. 20. Donnelly J, Czosnyka M, Sudhan N, Varsos GV, Nasr N, Jalloh I, Liu X, Dias C, Sekhon MS, Carpenter KL, Menon DK, Hutchinson PJ, Smielewski P. Increased Blood Glucose is Related to Disturbed Cerebrovascular Pressure Reactivity After Traumatic Brain Injury. Neurocrit Care. 2015 Feb;22(1):20-5. 21. Varsos GV, Budohoski KP, Kolias AG, Liu X, Smielewski P, Varsos VG, Hutchinson PJ, Pickard JD, Czosnyka M. Relationship of Vascular Wall Tension and Autoregulation Following Traumatic Brain Injury. Neurocrit Care. 2014 Oct;21(2):266-74. 22. Cabella Brenno, Donnelly Joseph, Cardim Danilo, Liu Xiuyun, Cabeleira Manuel, Smielewski Peter, Haubrich Christina, Hutchinson Peter, Kim Dong Joo, Czosnyka Marek. An association between ICP-derived data and outcome in TBI patients: The role of sample size. Journal of Neurocritical Care, 2016.